Qiao Z K, Halliday M L, Coates R A, Rankin J G
Canadian Liver Foundation Epidemiology Unit, Department of Preventive Medicine and Biostatistics, University of Toronto, Ontario.
Int J Epidemiol. 1988 Jun;17(2):414-8. doi: 10.1093/ije/17.2.414.
The relationship between liver cirrhosis death rates and certain nutritional factors was studied in 38 countries where mortality statistics were considered to be reliable. A partial correlation analysis showed that several food commodity consumption factors were independently and negatively (p less than 0.01) associated with liver cirrhosis death rates after adjustment for alcohol consumption. These factors were total calories, protein, fat, calcium, vitamin A and vitamin B2. The significant association of protein, vitamin A, vitamin B2 and calcium with the cirrhosis death rates is of importance since they were not intercorrelated with alcohol consumption. Further results showed that animal protein was more significantly related to cirrhosis death rates than vegetable protein. However, in view of certain limitations of this study, the findings do not necessarily reflect causal relationships but rather support the consideration by scientists that protein and vitamin deficiency may have certain effects on liver cirrhosis.
在38个被认为死亡率统计可靠的国家中，研究了肝硬化死亡率与某些营养因素之间的关系。偏相关分析表明，在调整酒精摄入量后，几种食品商品消费因素与肝硬化死亡率独立且呈负相关（p小于0.01）。这些因素包括总热量、蛋白质、脂肪、钙、维生素A和维生素B2。蛋白质、维生素A、维生素B2和钙与肝硬化死亡率的显著关联很重要，因为它们与酒精摄入量不存在相互关联。进一步的结果表明，动物蛋白比植物蛋白与肝硬化死亡率的关系更显著。然而，鉴于本研究存在某些局限性，这些发现不一定反映因果关系，而是支持科学家们的观点，即蛋白质和维生素缺乏可能对肝硬化有一定影响。
