Department of Laboratory Medicine, Manipal Hospital, Bengaluru, Karnataka, India.
Int J Lab Hematol. 2021 Aug;43(4):538-546. doi: 10.1111/ijlh.13607. Epub 2021 May 25.
Dysgranulopoiesis is a condition in which granulocytic production is defective and is most often described in neoplastic conditions. However, it can also be frequently seen in non-neoplastic conditions. Early suspicion and detection of these non-neoplastic causes may prevent further invasive and expensive interventions. In this review, we take a look at the various causes of dysgranulopoiesis with an emphasis on non-neoplastic etiologies, followed by a detailed outline of the laboratory approach for determining its many causes.
粒细胞生成障碍是一种粒细胞生成缺陷的病症，通常在肿瘤性疾病中描述。然而，它也可以经常在非肿瘤性疾病中看到。早期怀疑和检测这些非肿瘤性原因可能会防止进一步的侵入性和昂贵的干预措施。在这篇综述中，我们着眼于粒细胞生成障碍的各种原因，重点介绍非肿瘤性病因，并详细概述确定其许多病因的实验室方法。
