Department of Neurology, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Republic of Korea.
Medicine (Baltimore). 2021 May 28;100(21):e25696. doi: 10.1097/MD.0000000000025696.
Free-floating thrombi in the intracranial artery are rare. We report a case of a free-floating and spinning thrombus caused by turbulent flow distal to the basilar artery stenosis. We compare thrombus changes in a series of images according to time and describe the approach to treatment and thrombosis resolution..
A 55-year-old man presented to the emergency department on March 21, 2020, with left-sided weakness, bilateral limb ataxia, and a one-day history of dysarthria. Brain magnetic resonance imaging showed multifocal infarctions in the pons and cerebellum with severe basilar stenosis.
Digital subtraction angiography showed severe focal stenosis. A relatively large oval-shaped mobile thrombus was observed spinning due to turbulent flow at the distal portion of the stenosis.
We administered a combination antithrombotic regimen of warfarin and clopidogrel for 50 days.
No thrombus was observed on the third follow-up digital subtraction angiography.
No previous study has directly observed a mobile thrombus in the intracranial artery using digital subtraction angiography. We used a combination antithrombotic strategy, which was effective after long-term, rather than short-term, use.
颅内动脉中的游离血栓很少见。我们报告了一例由基底动脉狭窄远端湍流引起的游离和旋转血栓。我们根据时间比较了一系列图像中的血栓变化,并描述了治疗方法和血栓溶解情况。
一名 55 岁男性于 2020 年 3 月 21 日因左侧无力、双侧肢体共济失调和 1 天言语不清就诊于急诊科。脑磁共振成像显示桥脑和小脑多发性梗死,基底动脉严重狭窄。
数字减影血管造影显示严重的局灶性狭窄。在狭窄的远端,由于湍流,观察到一个相对较大的椭圆形移动血栓旋转。
我们给予华法林和氯吡格雷联合抗栓治疗 50 天。
第三次随访数字减影血管造影未见血栓。
以前没有研究使用数字减影血管造影直接观察颅内动脉中的移动血栓。我们使用了一种联合抗栓策略,这种策略在长期而非短期使用后是有效的。