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[快速康复时代的重建性食管手术]

[Reconstructive esophageal surgery in fast track epoch].

作者信息

Shestakov A L, Tarasova I A, Tskhovrebov A T, Boeva I A, Bitarov T T, Bezaltynnykh A A, Shakhbanov M E, Dergunova A P, Vasilyeva E S

机构信息

Petrovsky Russian Scientific Center of Surgery, Moscow, Russia.

出版信息

Khirurgiia (Mosk). 2021(6. Vyp. 2):73-83. doi: 10.17116/hirurgia202106273.

DOI:10.17116/hirurgia202106273
PMID:34032792
Abstract

OBJECTIVE

To evaluate an efficiency and safety of perioperative fast track management in reconstructive esophageal surgery.

MATERIAL AND METHODS

Perioperative fast track management protocol in reconstructive esophageal surgery has been applied since 2014 at the Department of Thoracoabdominal Surgery and Oncology of the Petrovsky Russian Scientific Center of Surgery. These patients (2017-2020) were included in the main group (=75). Patients who underwent traditional perioperative care (2010-2013) were enrolled in the control group (=63). The primary outcome was postoperative hospital-stay. We also evaluated ICU stay, incidence of complications according to Clavien-Dindo grading system with particular registration of respiratory complications, mortality, enteral and oral feeding onset.

RESULTS

There were no significant between-group differences in sex, age, ASA grade, body mass index. Fast track management reduced hospital-stay from 14 (12; 17) days in the control group to 11 (8; 22) days in the main group (=0.008). Mean ICU-stay decreased up to 1 (0.8; 2) day in the main group compared to the control group (4.1 (3.5; 5.6) days, <0.0001). Pneumonia was noted in 5 patients after fast track recovery and 15 patients in the control group (=0.004). No patients died in the main group, 3 (4.8%) patients - in the control group (=1).

CONCLUSION

Modern perioperative fast track management protocol is safe and effective for extensive reconstructive esophageal interventions. This approach reduces hospital-stay and ICU stay, as well as the incidence of respiratory complications.

摘要

目的

评估重建性食管手术围手术期快速康复管理的有效性和安全性。

材料与方法

自2014年起,俄罗斯彼得罗夫斯基外科科学中心胸腹部外科与肿瘤学部在重建性食管手术中应用围手术期快速康复管理方案。将2017 - 2020年的这些患者纳入主要组(n = 75)。将接受传统围手术期护理(2010 - 2013年)的患者纳入对照组(n = 63)。主要结局指标为术后住院时间。我们还评估了重症监护病房(ICU)住院时间、根据Clavien - Dindo分级系统的并发症发生率,特别记录了呼吸并发症、死亡率、肠内和口服喂养开始时间。

结果

两组在性别、年龄、美国麻醉医师协会(ASA)分级、体重指数方面无显著差异。快速康复管理使对照组的住院时间从14(12;17)天缩短至主要组的11(8;22)天(P = 0.008)。与对照组(4.1(3.5;5.6)天)相比,主要组的平均ICU住院时间减少至1(0.8;2)天(P < 0.0001)。快速康复组有5例患者发生肺炎,对照组有15例患者发生肺炎(P = 0.004)。主要组无患者死亡,对照组有3例(4.8%)患者死亡(P = 1)。

结论

现代围手术期快速康复管理方案对于广泛的重建性食管手术是安全有效的。这种方法可缩短住院时间和ICU住院时间,以及降低呼吸并发症的发生率。

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