Boumparis Nikolaos, Schulte Mieke H, Kleiboer Annet, Huizink Anja, Riper Heleen
Department of Clinical, Neuro and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
JMIR Res Protoc. 2021 Jun 7;10(6):e29750. doi: 10.2196/29750.
Young adults' drinking habits commonly exceed recommendations for low-risk drinking, which may have a negative effect on their mental, social, and physical health. As smartphones are highly accessible to young adults, mobile apps could be used to support young adults to develop low-risk drinking habits and improve their general health.
The objective of this study is to evaluate the effectiveness of Boozebuster, a self-guided mobile app based on healthy lifestyle-related components that aim to develop and maintain low-risk drinking habits among young adults.
This two-arm, parallel-group randomized controlled trial will investigate whether a 6-week self-guided mobile intervention (Boozebuster) targeting drinking behavior is more effective than a minimal intervention consisting of an educational website on alcohol use and its consequences for young adults. We will recruit 506 young adults (aged 18-30 years) from the Netherlands via an open recruitment strategy by using an open access website. All outcomes will be self-assessed through questionnaires. The primary outcome is the quantity and frequency of alcohol consumption in standard drinks (10 g ethanol per standard drink) per month (timeline follow-back [TLFB]). Secondary outcomes include binge-drinking sessions per month, alcohol-related problem severity (Rutgers Alcohol Problem Index), cannabis use frequency and quantity in grams (TLFB), depressive symptoms (Center for Epidemiological Studies Depression Scale), perceived stress (Perceived Stress Scale), engagement (Twente Engagement with eHealth Technologies Scale), readiness to change (Readiness to Change Questionnaire), mental well-being (Warwick-Edinburgh Mental Wellbeing Scale), trauma and COVID-19-related trauma (Short-Form Posttraumatic Stress Disorder Checklist for Diagnostic and Statistical Manual of Mental Disorders, 5th Edition), impulsivity (Urgency, Premeditation, Perseverance, Sensation Seeking, Positive Urgency Impulsive Behavior Scale), study or work performance (Individual Work Performance Questionnaire), and treatment adherence. Baseline (T0), 6-week postbaseline (T1), and 3-month postbaseline (T2) assessments will be conducted and analyzed on the basis of the intention-to-treat principle using multilevel mixed modeling analyses.
Recruitment began in September 2020. We received 933 registrations via our study information website; 506 participants have completed the T0 assessment, 336 participants have completed the T1 assessment, and 308 participants have completed the T2 assessment as of May 2021. The study is still in progress, and results will be reported in 2021 and 2022.
Self-guided mobile interventions based on a lifestyle approach might be an attractive approach for young adults due to their preference on self-reliance, healthy living, and increased perceived anonymity. Such interventions are yet understudied, and it is known that interventions addressing solely problem drinking are less appealing to young adults. We hypothesize that the Boozebuster mobile app will effectively reduce drinking levels compared to an alcohol educational website (control condition). If effective, our intervention could be an inexpensive and scalable public health intervention to improve drinking habits in young adults.
Netherlands Trial Register NL8828; https://www.trialregister.nl/trial/8828.
INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/29750.
年轻人的饮酒习惯通常超过低风险饮酒的建议标准，这可能会对他们的心理、社交和身体健康产生负面影响。由于年轻人很容易接触到智能手机，因此可以利用移动应用程序来帮助年轻人养成低风险饮酒习惯并改善他们的整体健康状况。
本研究的目的是评估一款名为“戒酒卫士”（Boozebuster）的自我引导式移动应用程序的有效性，该应用程序基于与健康生活方式相关的组件，旨在帮助年轻人养成并维持低风险饮酒习惯。
这项双臂、平行组随机对照试验将调查针对饮酒行为的为期6周的自我引导式移动干预（戒酒卫士）是否比仅包含一个关于酒精使用及其对年轻人影响的教育网站的最小干预更有效。我们将通过一个开放获取网站，采用开放招募策略，从荷兰招募506名年轻人（年龄在18至30岁之间）。所有结果都将通过问卷调查进行自我评估。主要结果是每月以标准饮酒单位（每标准饮酒单位含10克乙醇）计算的酒精消费量和饮酒频率（时间线回溯法[TLFB]）。次要结果包括每月的暴饮次数、与酒精相关的问题严重程度（罗格斯酒精问题指数）、大麻使用频率和以克为单位的使用量（TLFB）、抑郁症状（流行病学研究中心抑郁量表）、感知压力（感知压力量表）、参与度（特温特电子健康技术参与度量表）、改变意愿（改变意愿问卷）、心理健康（沃里克-爱丁堡心理健康量表）、创伤及与新冠疫情相关的创伤（《精神疾病诊断与统计手册》第5版创伤后应激障碍检查表简版）、冲动性（冲动性、预谋性、坚持性、感觉寻求、积极冲动行为量表）、学习或工作表现（个人工作表现问卷）以及治疗依从性。将基于意向性分析原则，使用多级混合模型分析进行基线（T0）、基线后6周（T1）和基线后3个月（T2）的评估并进行分析。
结果：招募工作于2020年9月开始。我们通过研究信息网站收到了933份注册申请；截至2021年5月，506名参与者完成了T0评估，336名参与者完成了T1评估，308名参与者完成了T2评估。该研究仍在进行中，结果将于2021年和2022年公布。
结论：基于生活方式的自我引导式移动干预可能因其对年轻人自力更生、健康生活以及更高的匿名感的偏好，而成为一种有吸引力的方法。此类干预措施尚未得到充分研究，而且已知仅针对问题饮酒的干预措施对年轻人的吸引力较小。我们假设与酒精教育网站（对照条件）相比，戒酒卫士移动应用程序将有效降低饮酒量。如果有效，我们的干预措施可能是一种低成本且可扩展的公共卫生干预措施，用于改善年轻人的饮酒习惯。
试验注册：荷兰试验注册编号NL8828；https://www.trialregister.nl/trial/8828。
国际注册报告识别码（IRRID）：DERR1-10.2196/29750。
