Physiotherapy Department, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, Brasil.
Physiotherapy Department, Universidade de Cruz Alta (UNICRUZ), Cruz Alta, Brasil.
Disabil Rehabil. 2022 Aug;44(16):4179-4188. doi: 10.1080/09638288.2021.1900929. Epub 2021 May 25.
Reviewing systematically the randomized controlled trials (RCTs) that evaluated aerobic exercisealone vs. usual care in exercise tolerance, functional capacity, and quality of life (QoL) in patients withpre-dialysis.
Searches in the MEDLINE, Cochrane CENTRAL, EMBASE, PEDro, and LILACS databases untilFebruary 2021 included RCTs that evaluated the effects of aerobic exercise on peak VO, functional capacity,lower limb muscle strength, and QoL. The random effect meta-analysis model was used andreported as mean difference (MD) and 95% confidence interval (CI), risk of bias through RoB2.0 and thequality of evidence by GRADE.
10 RCTs, with 365 patients. Aerobic exercise increased 2.07 ml/kg/min (95% CI = 1.16 to 2.98; I2= 24%, QoE moderate) at peak VO; 77.78m (95% CI= 33.27 to 122.30; I2= 44.5%, QoE moderate) in the 6MWT and 7.65 repetitions (95% CI= 5.73 to 9.58; I2= 0 %; QoE moderate) in STS-30 versus usual care. In QoL, studies reported improvements in the questionnaire scores. = 24%, QoE moderado) no pico de VO; 77,78 m (IC95% = 33,27-122,30; = 44,5%, QoE moderado) nas repetições 6MWT e 7,65 (IC95% = 5,73-9,58; = 0%; QoE moderado) em STS-30".
Aerobic exercise increases VO peak, functional capacity and lower limb muscle strength in patients with pre-dialysis. Effects on QoL appear to be beneficial.IMPLICATIONS FOR REHABILITATIONAerobic exercise should be encouraged in the rehabilitation of patients at any stage of chronic kidney disease.Aerobic exercise promotes improved exercise tolerance, functional capacity, and muscle strength of the lower limbs.There is some evidence to show it is beneficial to improve the quality of life.
系统回顾评估预透析患者单纯有氧锻炼与常规治疗相比在运动耐量、功能能力和生活质量（QoL）方面的随机对照试验（RCT）。
检索 MEDLINE、Cochrane 中心、EMBASE、PEDro 和 LILACS 数据库，纳入截至 2021 年 2 月评估有氧锻炼对峰值 VO、功能能力、下肢肌肉力量和 QoL 影响的 RCT。使用随机效应荟萃分析模型，报告均值差（MD）和 95%置信区间（CI），通过 RoB2.0 评估偏倚风险，通过 GRADE 评估证据质量。
纳入 10 项 RCT，共 365 例患者。与常规治疗相比，有氧锻炼可使峰值 VO 增加 2.07ml/kg/min（95%CI=1.16 至 2.98；I²=24%，证据质量中等）；6MWT 增加 77.78m（95%CI=33.27 至 122.30；I²=44.5%，证据质量中等）；STS-30 重复次数增加 7.65 次（95%CI=5.73 至 9.58；I²=0%，证据质量中等）。在 QoL 方面，研究报告了问卷评分的改善。
有氧锻炼可增加预透析患者的峰值 VO、功能能力和下肢肌肉力量。对 QoL 的影响似乎有益。
在慢性肾脏病的任何阶段，都应鼓励患者进行有氧锻炼。有氧锻炼可提高运动耐量、功能能力和下肢肌肉力量。有一些证据表明，它有益于改善生活质量。
