Li W J, Huang N, Zhang S C, Ma D X, Yang Y Q, Zhu R F
Department of Allergy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Zhonghua Yu Fang Yi Xue Za Zhi. 2021 May 6;55(5):620-626. doi: 10.3760/cma.j.cn112150-20210312-00248.
To investigate the species and concentrations of airborne pollens in Wuhan urban area and their correlation with the number of visits of allergic rhinitis patients. Retrospective analysis of pollen dispersal characteristics and the number of patients with allergic rhinitis presenting to Tongji Hospital of Huazhong University of Science and Technology in Wuhan city from October 2017 to September 2018, as well as pollen allergen testing results of patients with allergic rhinitis presenting to the Department of Allergy during the same period. Pollen data was collected by a 1-year air sampling conducted in Wuhan City during the same period using the volumetric method. The samples were examined microscopically to identify airborne pollen species and counted, and the concentrations of various pollens were calculated. Information on patients with allergic rhinitis who came to the hospital during the same period was collected, and the correlation between pollen concentration and the number of patient visits was statistically analyzed using Pearson correlation analysis. A total of 35 types of airborne pollen were collected from October 2017 to September 2018. The dominant pollens in spring were (68.46%, 1 042/1 522), (12.22%, 186/1 522) and (2.30%, 35/1 522); in summer and autumn, the dominant pollens were (3.81%, 58/1 522), (4.01%, 61/1 522) and (0.59%, 9/1 522). The peak number of visits for allergic rhinitis patients occurred in March-April and July-September, both exceeding 2 200 visits and reaching a maximum of 2 545 visits. There was a very weak correlation between the number of visits and the total pollen concentration (0.17, 0.001). The average monthly pollen skin prick test positive rate of patients with allergic rhinitis was highest in March-May, exceeding 40% with a maximum of 45.73%, and there was a significant correlation between the positive pollen skin prick test positive rate and the average monthly pollen concentration (0.62, 0.031). Pollen species and concentrations fluctuated continuously with time in Wuhan urban area, with peak pollen dispersal in spring from March to April and in autumn from August to September. The number of visits to patients with allergic rhinitis and the positive pollen skin prick test positive rate increased accordingly during the peak pollen concentration periods.
调查武汉市城区空气传播花粉的种类、浓度及其与过敏性鼻炎患者就诊人次的相关性。回顾性分析2017年10月至2018年9月在武汉市华中科技大学同济医学院附属同济医院就诊的过敏性鼻炎患者的花粉飘散特征、就诊人次以及同期在过敏科就诊的过敏性鼻炎患者的花粉变应原检测结果。同期在武汉市采用容量法进行为期1年的空气采样收集花粉数据。对样本进行显微镜检查以鉴定空气传播花粉的种类并计数，计算各种花粉的浓度。收集同期来院就诊过敏性鼻炎患者的信息，采用Pearson相关分析对花粉浓度与患者就诊人次之间的相关性进行统计学分析。2017年10月至2018年9月共收集到35种空气传播花粉。春季优势花粉为（68.46%，1042/1522）、（12.22%，186/1522）和（2.30%，35/1522）；夏秋季节优势花粉为（3.81%，58/1522）、（4.01%，61/1522）和（0.59%，9/1522）。过敏性鼻炎患者就诊人次高峰出现在3-4月和7-9月，均超过2200人次，最高达2545人次。就诊人次与花粉总浓度之间存在非常弱的相关性（0.17，0.001）。过敏性鼻炎患者花粉皮肤点刺试验平均月阳性率在3-5月最高，超过40%，最高达45.73%，花粉皮肤点刺试验阳性率与月平均花粉浓度之间存在显著相关性（0.62，0.031）。武汉市城区花粉种类和浓度随时间不断波动，花粉飘散高峰在春季3-4月和秋季8-9月。在花粉浓度高峰期，过敏性鼻炎患者就诊人次及花粉皮肤点刺试验阳性率相应增加。
