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从 叶片中分离得到两个新的三萜糖苷。

Two new triterpenoid glycosides from leaves of .

机构信息

Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, People's Republic of China.

Hunan Cancer Hospital, Changsha, People's Republic of China.

出版信息

Nat Prod Res. 2022 Oct;36(20):5277-5282. doi: 10.1080/14786419.2021.1931182. Epub 2021 May 25.

Abstract

Two dammarane glycosides () were isolated from the leaves of . The structures of new compounds were established by application of spectroscopic methods, including one-dimensional and two-dimensional NMR, HRESIMS, and chemical hydrolysis. When evaluated against seven human cancer cell lines, the two compounds exhibited selective cytotoxicity to MCF-7 cells.[Formula: see text].

摘要

从 的叶子中分离得到两种达玛烷型糖苷()。新化合物的结构通过应用包括一维和二维 NMR、HRESIMS 以及化学水解在内的光谱方法确定。当对七种人癌细胞系进行评价时,这两种化合物对 MCF-7 细胞表现出选择性细胞毒性。[化学式:见正文]。

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