分析全国 1400 万儿童住院数据中慢性肾脏病的发病情况。
Analysis of chronic kidney disease among national hospitalization data with 14 million children.
机构信息
Department of Pediatrics, Peking University First Hospital, Beijing, China.
China Standard Medical Information Research Center, Shenzhen, China.
出版信息
BMC Nephrol. 2021 May 25;22(1):195. doi: 10.1186/s12882-021-02383-1.
BACKGROUND
The main purpose was to determine basic epidemiological data on CKD among hospitalized pediatric patients in China.
METHODS
Data from pediatric inpatients with CKD hospitalized from June 1, 2013 to May 31, 2017 were extracted from the electronic records of HQMS database, which includes over 14 million inpatients. Codes from the 10th revision of the International Classification of Diseases (ICD-10) were used to search the database.
RESULTS
A total of 524 primary diseases of CKD were included in this study. In all, there were 278 231 pediatric inpatients with CKD, which accounted for 1.95 % of the 14 250 594 pediatric inpatients registered in the HQMS database. The number of pediatric inpatients with CKD was 67 498 in 2013, 76 810 in 2014, 81 665 in 2015 and 82 649 in 2016, which accounted for 1.93 %, 1.93 %, 1.99 and 2.09 %, respectively, of the total population of pediatric inpatients. The etiology of CKD was secondary nephrosis in 37.95 % of cases, which ranked first and followed by CAKUT with a percentage of 24.61 %. Glomerular diseases and cystic kidney disease accounted for 21.18 and 5.07 %, respectively. Among all 278 231 patients, 6 581 (2.37 %) had a primary discharge diagnosis of CKD. The renal pathology findings of CKD showed that IgA accounted for 51.17 %.
CONCLUSIONS
This study provides a descriptive analysis of the hospitalized population of pediatric CKD patients. Our study provides important, fundamental data for policy making and legislation, registry implementation and the diagnosis, treatment and prevention of CKD in China.
背景
本研究旨在确定中国住院儿科患者慢性肾脏病（CKD）的基本流行病学数据。
方法
从 HQMS 数据库的电子病历中提取 2013 年 6 月 1 日至 2017 年 5 月 31 日期间住院的 CKD 儿科患者的数据，该数据库包含超过 1400 万住院患者。使用国际疾病分类第 10 次修订版（ICD-10）的代码对数据库进行搜索。
结果
本研究共纳入 524 种 CKD 主要疾病。共有 278 231 例 CKD 儿科住院患者，占 HQMS 数据库中登记的 14250594 例儿科住院患者的 1.95%。2013 年、2014 年、2015 年和 2016 年 CKD 儿科住院患者分别为 67498 例、76810 例、81665 例和 82649 例，占当年儿科住院患者总数的 1.93%、1.93%、1.99%和 2.09%。CKD 的病因是继发性肾病，占 37.95%，位居第一，其次是 CAKUT，占 24.61%。肾小球疾病和囊性肾病分别占 21.18%和 5.07%。在所有 278231 例患者中，有 6581 例（2.37%）患者的主要出院诊断为 CKD。CKD 的肾脏病理检查结果显示，IgA 占 51.17%。
结论
本研究对住院儿科 CKD 患者人群进行了描述性分析。我们的研究为中国制定政策法规、实施登记制度以及 CKD 的诊断、治疗和预防提供了重要的基础数据。
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