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孕妇中艾滋病毒流行率的异质性和局限性要求采取分散式艾滋病毒干预措施:对卡纳塔克邦三轮艾滋病毒哨点监测(2013 - 2017年)数据的分析

Heterogeneity and Confinement of HIV Prevalence among Pregnant Women Calls for Decentralized HIV Interventions: Analysis of Data from Three Rounds of HIV Sentinel Surveillance in Karnataka: 2013-2017.

作者信息

Aridoss Santhakumar, Mathiyazhakan Malathi, Jaganathasamy Nagaraj, Balsubramanian Ganesh, Natesan Manikandan, Padmapriya V M, David Joseph K, Kumar Pradeep, Arumugam Elangovan

机构信息

Scientist, HIV Surveillance, Chennai, Tamil Nadu, India.

Scientist D (Laboratory), ICMR National Institute of Epidemiology, Chennai, Tamil Nadu, India.

出版信息

Indian J Community Med. 2021 Jan-Mar;46(1):121-125. doi: 10.4103/ijcm.IJCM_68_20. Epub 2021 Mar 1.

Abstract

BACKGROUND

The HIV sentinel surveillance (HSS) serves to estimate the levels and trend of HIV prevalence among high-risk, bridge, and general population and monitors HIV management at national, state, and district levels. Data from HSS are valuable in understanding the risk factors associated with HIV transmission with particular demographic characteristics.

OBJECTIVES

The objective was to analyze the sociodemographic profile of the pregnant mothers attending the antenatal care (ANC) clinics in Karnataka, in order to understand the dynamics of HIV within the general population in Karnataka.

MATERIALS AND METHODS

Study design: this was a cross-sectional study conducted using consecutive sampling method. Study setting: the surveillance was conducted at select antenatal clinics, in Karnataka, India, between January and March, in the years 2013, 2015, and 2017. Methodology: in total, 74,278 eligible pregnant women aged between 15 and 49 years, attending the sentinel sites for the first time during the surveillance period, were included in the study. Information on their sociodemographic characteristics and blood samples was collected.

RESULTS

HIV prevalence among the ANC clinic attendees has significantly declined, reaching a recent stabilization. The risk factors significantly associated with HIV among pregnant women were age, education, occupation, and marital status. HIV is highly concentrated in the northern and southern districts of Karnataka.

CONCLUSION

Despite the declining trends of HIV prevalence in Karnataka, the epidemic is heterogeneous and concentrated within the state, calling for decentralized region-specific interventions.

摘要

背景

艾滋病哨点监测(HSS)用于估计高危人群、桥梁人群和普通人群中的艾滋病病毒流行水平及趋势,并在国家、邦和地区层面监测艾滋病病毒管理情况。HSS数据对于了解与特定人口特征相关的艾滋病病毒传播风险因素具有重要价值。

目的

分析卡纳塔克邦产前保健(ANC)诊所就诊孕妇的社会人口学特征,以了解卡纳塔克邦普通人群中的艾滋病病毒动态。

材料与方法

研究设计:这是一项采用连续抽样方法进行的横断面研究。研究地点:监测于2013年、2015年和2017年1月至3月期间在印度卡纳塔克邦选定的产前诊所进行。方法:总共纳入了74278名年龄在15至49岁之间、在监测期间首次到哨点就诊的符合条件的孕妇。收集了她们的社会人口学特征信息和血样。

结果

ANC诊所就诊者中的艾滋病病毒流行率显著下降,近期趋于稳定。与孕妇艾滋病病毒感染显著相关的风险因素包括年龄、教育程度、职业和婚姻状况。艾滋病病毒高度集中在卡纳塔克邦的北部和南部地区。

结论

尽管卡纳塔克邦的艾滋病病毒流行率呈下降趋势,但该流行病具有异质性且在该邦内集中,需要采取分散的针对特定地区的干预措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/150b/8117896/e6caa7f869a5/IJCM-46-121-g001.jpg

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