Post-Graduate Program in Dentistry (Prosthodontics), School of Health and Life Sciences, Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, Brazil.
Post-Graduate Program in Dentistry (Restorative Dentistry), School of Health and Life Sciences, Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, Brazil.
J Prosthodont. 2021 Oct;30(8):656-664. doi: 10.1111/jopr.13394. Epub 2021 Jun 7.
This systematic review and meta-analysis of in vitro studies compared the prepolymerized acrylic resin used for CAD/CAM complete denture manufacturing versus the heat-polymerized acrylic resin for conventional complete dentures in terms of surface roughness, wettability, hardness and flexural strength.
An electronic search was performed in the PubMed, Embase, LILACS and Web of Science databases, without language or date restrictions. Gray literature and manual search tools were also used. The systematic review was carried out by two researchers independently, following the inclusion criteria: in vitro studies testing the CAD/CAM acrylic resin with a control group of heat-polymerized acrylic resin which compared at least one of the four material properties above. The meta-analysis was performed separately for each property, using a random effect model.
Of the 914 studies found by means of search strategies, 698 were selected for the systematic review. After applying the eligibility criteria, only 17 articles were selected for the qualitative analysis in the systematic review; among these, 14 were included in the quantitative meta-analysis. The CAD/CAM prepolymerized acrylic resin in blocks had similar properties when compared to heat-polymerized acrylic resin in almost all outcome measures, with the exception of a statistically significant reduction in surface roughness.
Based on the findings of this systematic review and meta-analysis, equally satisfactory results can be expected from dental prosthesis manufactured by the CAD/CAM system when compared to conventional ones, with the additional potential of reducing the pigmentation and attached microorganisms due to the reduced surface roughness of the prepolymerized resin.
本系统评价和荟萃分析对体外研究进行了比较，比较了用于 CAD/CAM 全口义齿制作的预聚物丙烯酸树脂与用于传统全口义齿的热聚合丙烯酸树脂在表面粗糙度、润湿性、硬度和弯曲强度方面的性能。
对 PubMed、Embase、LILACS 和 Web of Science 数据库进行了电子检索，不限制语言和日期。还使用了灰色文献和手动检索工具。系统评价由两名研究人员独立进行，遵循纳入标准：体外研究测试 CAD/CAM 丙烯酸树脂，对照组为热聚合丙烯酸树脂，比较了上述四项材料性能中的至少一项。荟萃分析分别针对每种性能进行，使用随机效应模型。
通过搜索策略共发现 914 篇研究，其中 698 篇被选为系统评价。在应用纳入标准后，仅有 17 篇文章被选为系统评价的定性分析；其中，有 14 篇被纳入定量荟萃分析。在几乎所有的测量指标中，块状 CAD/CAM 预聚物丙烯酸树脂与热聚合丙烯酸树脂的性能相似，除了表面粗糙度的统计学显著降低外。
基于本系统评价和荟萃分析的结果，与传统义齿相比，CAD/CAM 系统制作的义齿可获得同样令人满意的结果，且由于预聚物树脂的表面粗糙度降低，还可能减少色素沉着和附着的微生物。
