Moore B D, Papanicolaou A C
Division of Neurosurgery, University of Texas Medical Branch, Galveston 77550.
J Clin Exp Neuropsychol. 1988 Aug;10(4):380-6. doi: 10.1080/01688638808408246.
A dichotic-listening procedure was used to investigate the role of the right hemisphere in recovery from aphasia following left-hemisphere stroke. Thirty-one stroke patients were divided into three groups: (a) patients who were recovering from aphasia (Aphasic group, n = 11), (b) patients who had experienced mild strokes with only transient dysarthria (Dysarthric group, n = 10), and (c) patients who had sustained right-hemisphere stroke with no language disturbance (Nonaphasic group, n = 10). In addition, a group of normal, healthy volunteers served as a control group (n = 11). Results show that, like the Control subjects, the Dysarthrics and Nonaphasics showed a strong right-ear advantage (REA) for dichotically presented consonant-vowel (CV) syllables. This is usually thought to be an indication of left-hemisphere dominance (Kimura, 1961). By contrast, the Aphasic group showed left-ear advantage (LEA) suggesting a shift in cerebral dominance for language. The possibility that the results were due to sensory degradation of the auditory messages (lesion effect) was explored. This idea was rejected in favor of an explanation based on increased right-hemisphere mediation of language following left-hemisphere aphasiogenic lesions.
采用双耳分听程序来研究右半球在左半球中风后失语症恢复过程中的作用。31名中风患者被分为三组：(a) 正在从失语症中恢复的患者（失语症组，n = 11），(b) 经历过轻度中风且仅有短暂构音障碍的患者（构音障碍组，n = 10），以及 (c) 患有右半球中风且无语言障碍的患者（非失语症组，n = 10）。此外，一组正常健康志愿者作为对照组（n = 11）。结果显示，与对照组受试者一样，构音障碍组和非失语症组在双耳分听呈现的辅音 - 元音（CV）音节时表现出强烈的右耳优势（REA）。这通常被认为是左半球优势的一个指标（木村，1961）。相比之下，失语症组表现出左耳优势（LEA），表明语言的大脑优势发生了转变。研究了结果是否由于听觉信息的感觉退化（病变效应）所致的可能性。该观点被否定，转而支持基于左半球致失语性病变后右半球对语言的介导作用增强的解释。
