Papanicolaou A C, Moore B D, Levin H S, Eisenberg H M
Arch Neurol. 1987 May;44(5):521-4. doi: 10.1001/archneur.1987.00520170049021.
A probe evoked potentials procedure was used to assess the relative engagement of both cerebral hemispheres during a language task in the following four groups of dextral adults: left hemisphere (LH)-damaged aphasics recovering from stroke, dysarthrics, right hemisphere (RH)-damaged nonaphasic patients, and normal control subjects. In agreement with previous findings using the probe procedure, the present results indicate greater task-specific RH activation in recovering aphasics and, to a lesser degree, dysarthric patients and greater LH activation in both nonaphasic, RH-damaged patients and normal control subjects. On the basis of these data, we suggest that increasing participation of the nondominant hemisphere may subserve restitution of language in adults sustaining LH lesions.
采用诱发电位程序，对四组右利手成年人在语言任务期间大脑两半球的相对参与情况进行评估：从卒中恢复的左半球（LH）损伤失语症患者、构音障碍患者、右半球（RH）损伤非失语症患者以及正常对照受试者。与先前使用诱发电位程序的研究结果一致，目前的结果表明，恢复中的失语症患者以及程度较轻的构音障碍患者在任务特定方面右侧半球激活程度更高，而在非失语症的右侧半球损伤患者和正常对照受试者中左侧半球激活程度更高。基于这些数据，我们认为非优势半球参与度的增加可能有助于左半球损伤成年人语言功能的恢复。
