Datarkar Abhay, Valvi Bhavana, Parmar Suraj, Patil Jagadish
Department of Oral and Maxillofacial Surgery, Government Dental College and Hospital, Nagpur, Maharashtra, 440003, India.
J Oral Biol Craniofac Res. 2021 Jul-Sep;11(3):410-414. doi: 10.1016/j.jobcr.2021.03.004. Epub 2021 Mar 26.
Distraction osteogenesis is a surgical technique of new bone formation between the osteotomized bone segments with the help of gradual incremental traction. As distraction osteogenesis is slow biologic process, soft tissue changes gradually follow the new bone formation. Mandibular distraction is one of the accepted modalities to treat the triad of TMJ ankylosis, obstructive sleep apnoea & micrognathia and also for facial asymmetry cases like hemifacial microsomia, mandibular hypoplasia etc. After the distraction osteogenesis, some relapse has been noticed in patients. Therefore, this study was conducted to assess the quality of the newly formed bone after distraction osteogenesis of mandible using 3 dimensional computed tomography (3DCT Scan) to evaluate its relation with relapse if any.
Total 5 patients of facial asymmetry reported to the Department of Oral and Maxillofacial Surgery were enrolled. Distraction osteogenesis of mandible was carried out in all the patients. Radiographic analysis (CT Scan) was done after 1 year of surgery for further planning and management of deformity. The non-distracted site was considered as a control side and it was compared with newly formed bone at distraction site. The standard & universally accepted radio density measuring Hounsfield Unit (HU) in 3DCT scan was calculated in axial,coronal, sagittal sections from distraction site and it was compared with non-distraction site, as Hounsfield unit is considered as a standard tool for measuring the bone density to evaluate the quality as well as quantity of newly formed bone.
The total mean Hounsfield Unit of distracted site of all three sections was 359.8 HU and non-distracted site was 545.2 HU. Statistical analysis was carried out using students paired test and p value was obtained which was <0.01 suggestive of statistically significant difference between the quality of bone in distracted site and non-distracted site.
The findings of our study concluded that the quality of bone formed after distraction osteogenesis was satisfactory but it was less mineralized with less dense trabecular pattern compared to non-distracted bone region of mandible which leads to some relapse. Therefore it was advisable to reinforce the distracted bone segment by cutting the activation arm of distractor itself or mini plate or reconstruction plate to prevent relapse.
牵张成骨是一种借助逐渐增加的牵引力在截骨后的骨段之间形成新骨的外科技术。由于牵张成骨是一个缓慢的生物学过程,软组织变化会逐渐跟随新骨形成。下颌骨牵张是治疗颞下颌关节强直、阻塞性睡眠呼吸暂停和小下颌三联征以及半侧颜面短小、下颌发育不全等面部不对称病例所公认的方法之一。在牵张成骨后,已注意到患者出现一些复发情况。因此,本研究旨在使用三维计算机断层扫描(3DCT扫描)评估下颌骨牵张成骨后新形成骨的质量,以评估其与复发(如有)的关系。
1)客观分析下颌骨牵张成骨后形成的骨质量。2)观察牵张完成后新形成骨的部位及结构。
共纳入5例到口腔颌面外科就诊的面部不对称患者。对所有患者进行下颌骨牵张成骨。术后1年进行影像学分析(CT扫描),以进一步规划和处理畸形。将未牵张部位作为对照侧,并与牵张部位新形成的骨进行比较。在3DCT扫描中,在牵张部位的轴向、冠状面和矢状面计算标准且普遍接受的用于测量骨密度的亨氏单位(HU),并与未牵张部位进行比较,因为亨氏单位被视为测量骨密度以评估新形成骨的质量和数量的标准工具。
所有三个层面牵张部位的总平均亨氏单位为359.8 HU,未牵张部位为545.2 HU。使用学生配对检验进行统计分析,得到的p值<0.01,表明牵张部位和未牵张部位的骨质量之间存在统计学显著差异。
我们的研究结果表明,牵张成骨后形成的骨质量令人满意,但与下颌骨未牵张的骨区域相比,其矿化程度较低,小梁模式密度较小,并导致了一些复发。因此,建议通过切断牵张器本身的激活臂或微型钢板或重建钢板来加强牵张的骨段,以防止复发。