Khera Sudeep, Elhence Poonam, Jayakumar D, Gupta Amit
Department of Pathology and Lab Medicine, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
Surgical Oncology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
J Family Med Prim Care. 2021 Feb;10(2):1047-1049. doi: 10.4103/jfmpc.jfmpc_1755_20. Epub 2021 Feb 27.
Follicular thyroid carcinoma (FTC) presenting as an isolated spinal metastasis with features of compression myelopathy is extremely rare with <10 cases reported in world literature. FTC is the second most common thyroid cancer with an indolent course. It predominantly occurs in females. The most common route of metastasis is through hematogenous routes to lung, liver, bones, etc., Herein we report a case of 47-year-old female presented with lesion involving sacral vertebrae and biopsy showing metastatic follicular carcinoma with morphology and immunohistochemistry of thyroid gland. The present case highlights the rarity of FTC to present as upfront solitary vertebral metastases with history of prior hemithyroidectomy. All the cases of spinal mass should be evaluated thoroughly to exclude any metastatic deposits.
以压迫性脊髓病为特征的孤立性脊柱转移滤泡状甲状腺癌极为罕见,世界文献报道不足10例。滤泡状甲状腺癌是第二常见的甲状腺癌,病程进展缓慢。它主要发生在女性。最常见的转移途径是通过血行转移至肺、肝、骨等部位。在此,我们报告一例47岁女性,其骶椎出现病变,活检显示为转移性滤泡癌,具有甲状腺的形态学和免疫组化特征。本病例凸显了滤泡状甲状腺癌以先前半甲状腺切除术后出现的孤立性椎体转移为首发表现的罕见性。所有脊柱肿块病例均应进行全面评估,以排除任何转移性病灶。