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孤立性脊柱转移伴脊髓压迫导致滤泡性甲状腺癌的诊断。

Isolated Spinal Metastasis with Spinal Cord Compression Leads to a Diagnosis of a Follicular Thyroid Carcinoma.

作者信息

Toshkezi Gentian, Galgano Michael, Libohova Silva, Marawar Satya

机构信息

Neurosurgery, SUNY Upstate Medical University.

Bachelor of Science, Temple University.

出版信息

Cureus. 2015 Oct 12;7(10):e346. doi: 10.7759/cureus.346.

Abstract

INTRODUCTION

Thyroid carcinoma initially presents with clinical symptoms due to metastatic lesions in less than 5% of cases. Spinal cord compression from an epidural metastatic lesion as a first symptom is extremely rare. One would expect such a presentation to occur much later in the course of the disease.

METHODS

We are presenting a case report of a follicular thyroid carcinoma that presented with spinal cord compression from a thoracic epidural metastatic lesion in a previously healthy 55-year-old male. A single metastasis of follicular thyroid carcinoma presenting with posterior spinal cord compression is rare. In this particular case, our management included a mid-thoracic laminectomy, followed by resection of the epidural lesion. Once the surgical pathology confirmed the diagnosis of a follicular thyroid carcinoma, the general surgery team performed a near total thyroidectomy, after which he received radioactive iodine therapy. The patient is symptom-free at his three-year follow-up.

CONCLUSION

Initial presentation of follicular thyroid carcinoma with symptomatic thoracic myelopathy from an epidural metastasis is very uncommon. An early diagnosis and prompt surgical intervention provided an excellent outcome.

摘要

引言

甲状腺癌最初因转移灶出现临床症状的情况不到5%。硬膜外转移灶导致脊髓压迫作为首发症状极为罕见。人们通常认为这种表现会在疾病进程的后期才出现。

方法

我们报告一例滤泡状甲状腺癌病例,该病例发生在一名55岁既往健康男性身上,表现为胸段硬膜外转移灶导致脊髓压迫。滤泡状甲状腺癌单个转移灶伴脊髓后索压迫较为罕见。在这个特殊病例中,我们的治疗包括胸段中部椎板切除术,随后切除硬膜外病灶。手术病理确诊为滤泡状甲状腺癌后,普通外科团队进行了近全甲状腺切除术,之后患者接受了放射性碘治疗。患者在三年随访时无症状。

结论

滤泡状甲状腺癌最初表现为硬膜外转移导致有症状的胸段脊髓病非常少见。早期诊断和及时的手术干预带来了良好的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/362d/4641720/644e9273e75f/cureus-0007-000000000346-i01.jpg

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