Groeneweg Jolijn W, Roze Joline F, Veldhuis Wouter B, Ruurda Jelle P, Gerestein Cornelis G, Zweemer Ronald P
Department of Gynecologic Oncology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Department of Radiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Gynecol Oncol Rep. 2021 May 7;37:100783. doi: 10.1016/j.gore.2021.100783. eCollection 2021 Aug.
Despite an often early diagnosis and effective initial surgical management, one third of adult granulosa cell tumors (aGCTs) eventually, and often repeatedly, recurs. Debulking surgery remains the preferred treatment modality for recurrent aGCT, although the risk of intraoperative complications increases with repeated laparotomy. Minimally invasive surgery may limit the risk of complications. We aim to share our initial experience with robotic debulking surgery for recurrent aGCT. Clinical and surgical data of patients with recurrent aGCT who underwent robotic cytoreductive surgery over a three-year period at a tertiary referral center were retrospectively collected and analyzed. Between 2017 and 2020, three patients underwent robotic debulking surgery for recurrent aGCT at our institution. Complete cytoreduction was achieved in all patients. No intraoperative or postoperative complications were reported. This small pilot series at a single academic institution suggests that robot-assisted laparoscopy may be feasible and safe in selected patients with recurrent aGCT. A minimally invasive approach could reduce the complexity of successive surgeries for aGCT relapse.
尽管成人颗粒细胞瘤（aGCT）通常能早期诊断且初始手术治疗有效，但仍有三分之一的患者最终会复发，且常常反复复发。肿瘤细胞减灭术仍是复发性aGCT的首选治疗方式，不过随着剖腹手术次数增加，术中并发症风险也会上升。微创手术或许能降低并发症风险。我们旨在分享我们在复发性aGCT机器人肿瘤细胞减灭术方面的初步经验。回顾性收集并分析了在一家三级转诊中心三年内接受机器人细胞减灭手术的复发性aGCT患者的临床和手术数据。2017年至2020年期间，我院有三名患者接受了复发性aGCT的机器人肿瘤细胞减灭术。所有患者均实现了完全细胞减灭。未报告术中或术后并发症。这个来自单一学术机构的小型试点系列研究表明，机器人辅助腹腔镜手术在部分复发性aGCT患者中可能是可行且安全的。微创方法可以降低aGCT复发后后续手术的复杂性。
