Ohta Mineto, Hara Yasuyuki, Kashiwadate Toshiaki, Chin Masahiro, Hagiwara Motohisa, Nakanishi Wataru, Ito Ken, Nishida Akiko, Hashizume Eiji
Department of Surgery, Nihonkai General Hospital, Yamagata, Japan.
Department of Gastroenterological Surgery, Graduate School of Medicine, Tohoku University, Sendai, Japan.
Case Rep Gastroenterol. 2021 Jul 9;15(2):639-644. doi: 10.1159/000515412. eCollection 2021 May-Aug.
Adult-type ovarian granulosa cell tumors (AGCTs) are very rare tumors that account for <5% of all ovarian carcinomas. AGCTs have low malignancy potential and rarely metastasize 5-30 years after the initial diagnosis. Because time has passed from the first surgery and because recurrence develops in various locations, the differential diagnosis is difficult. In particular, tumors developing in the greater omentum are encountered rarely, and it is necessary to carefully consider the differential diagnosis, including primary and secondary neoplasms. Although CT is useful to detect omental tumors, the diagnosis requires invasive procedures. We report a case of AGCT recurrence in the greater omentum that was resected during laparoscopic cholecystectomy. A patient visited our hospital with right-sided abdominal pain. The CT revealed gallbladder stones, a ureteral stone, and a right abdominal mass. The diagnosis of the abdominal tumor was difficult on the basis of blood biochemical testing, gastrointestinal endoscopy, or image inspection. Although the patient underwent several previous surgeries and there were no findings of malignancy with positron emission tomography, we chose to resect the tumor for combined diagnosis and treatment during laparoscopic cholecystectomy. Intraoperative findings showed that the tumor originated from the greater omentum, and the tumor was diagnosed as AGCT recurrence by pathology. A recurrence of AGCT in the greater omentum is very rare, and laparoscopic surgery was safe and useful for resection, in our case.
成人型卵巢颗粒细胞瘤(AGCTs)是非常罕见的肿瘤,占所有卵巢癌的比例不到5%。AGCTs的恶性潜能较低,在初次诊断后5至30年很少发生转移。由于距首次手术已过去较长时间,且复发发生在不同部位,鉴别诊断困难。特别是大网膜发生的肿瘤很少见,因此有必要仔细考虑鉴别诊断,包括原发性和继发性肿瘤。虽然CT有助于检测大网膜肿瘤,但诊断需要侵入性操作。我们报告一例在腹腔镜胆囊切除术期间切除的大网膜AGCT复发病例。一名患者因右侧腹痛前来我院就诊。CT显示有胆囊结石、输尿管结石和右侧腹部肿块。根据血液生化检查、胃肠内镜检查或影像学检查,难以诊断腹部肿瘤。尽管该患者此前接受过多次手术,且正电子发射断层扫描未发现恶性肿瘤迹象,但我们选择在腹腔镜胆囊切除术期间切除肿瘤以进行联合诊断和治疗。术中发现肿瘤起源于大网膜,经病理诊断为AGCT复发。大网膜AGCT复发非常罕见,在我们的病例中,腹腔镜手术对于切除是安全且有效的。