• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

成人颗粒细胞瘤术后11年大网膜复发

Recurrence of Adult Granulosa Cell Tumor in the Greater Omentum 11 Years after Surgery.

作者信息

Ohta Mineto, Hara Yasuyuki, Kashiwadate Toshiaki, Chin Masahiro, Hagiwara Motohisa, Nakanishi Wataru, Ito Ken, Nishida Akiko, Hashizume Eiji

机构信息

Department of Surgery, Nihonkai General Hospital, Yamagata, Japan.

Department of Gastroenterological Surgery, Graduate School of Medicine, Tohoku University, Sendai, Japan.

出版信息

Case Rep Gastroenterol. 2021 Jul 9;15(2):639-644. doi: 10.1159/000515412. eCollection 2021 May-Aug.

DOI:10.1159/000515412
PMID:34616269
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8454241/
Abstract

Adult-type ovarian granulosa cell tumors (AGCTs) are very rare tumors that account for <5% of all ovarian carcinomas. AGCTs have low malignancy potential and rarely metastasize 5-30 years after the initial diagnosis. Because time has passed from the first surgery and because recurrence develops in various locations, the differential diagnosis is difficult. In particular, tumors developing in the greater omentum are encountered rarely, and it is necessary to carefully consider the differential diagnosis, including primary and secondary neoplasms. Although CT is useful to detect omental tumors, the diagnosis requires invasive procedures. We report a case of AGCT recurrence in the greater omentum that was resected during laparoscopic cholecystectomy. A patient visited our hospital with right-sided abdominal pain. The CT revealed gallbladder stones, a ureteral stone, and a right abdominal mass. The diagnosis of the abdominal tumor was difficult on the basis of blood biochemical testing, gastrointestinal endoscopy, or image inspection. Although the patient underwent several previous surgeries and there were no findings of malignancy with positron emission tomography, we chose to resect the tumor for combined diagnosis and treatment during laparoscopic cholecystectomy. Intraoperative findings showed that the tumor originated from the greater omentum, and the tumor was diagnosed as AGCT recurrence by pathology. A recurrence of AGCT in the greater omentum is very rare, and laparoscopic surgery was safe and useful for resection, in our case.

摘要

成人型卵巢颗粒细胞瘤(AGCTs)是非常罕见的肿瘤,占所有卵巢癌的比例不到5%。AGCTs的恶性潜能较低,在初次诊断后5至30年很少发生转移。由于距首次手术已过去较长时间,且复发发生在不同部位,鉴别诊断困难。特别是大网膜发生的肿瘤很少见,因此有必要仔细考虑鉴别诊断,包括原发性和继发性肿瘤。虽然CT有助于检测大网膜肿瘤,但诊断需要侵入性操作。我们报告一例在腹腔镜胆囊切除术期间切除的大网膜AGCT复发病例。一名患者因右侧腹痛前来我院就诊。CT显示有胆囊结石、输尿管结石和右侧腹部肿块。根据血液生化检查、胃肠内镜检查或影像学检查,难以诊断腹部肿瘤。尽管该患者此前接受过多次手术,且正电子发射断层扫描未发现恶性肿瘤迹象,但我们选择在腹腔镜胆囊切除术期间切除肿瘤以进行联合诊断和治疗。术中发现肿瘤起源于大网膜,经病理诊断为AGCT复发。大网膜AGCT复发非常罕见,在我们的病例中,腹腔镜手术对于切除是安全且有效的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f726/8454241/247c4a98e5f9/crg-0015-0639-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f726/8454241/94d199bc77a1/crg-0015-0639-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f726/8454241/28ee082d72ad/crg-0015-0639-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f726/8454241/247c4a98e5f9/crg-0015-0639-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f726/8454241/94d199bc77a1/crg-0015-0639-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f726/8454241/28ee082d72ad/crg-0015-0639-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f726/8454241/247c4a98e5f9/crg-0015-0639-g03.jpg

相似文献

1
Recurrence of Adult Granulosa Cell Tumor in the Greater Omentum 11 Years after Surgery.成人颗粒细胞瘤术后11年大网膜复发
Case Rep Gastroenterol. 2021 Jul 9;15(2):639-644. doi: 10.1159/000515412. eCollection 2021 May-Aug.
2
Solitary fibrous tumor of the greater omentum, mimicking gastrointestinal stromal tumor of the small intestine: a case report.大网膜孤立性纤维瘤,酷似小肠胃肠道间质瘤:一例报告
Int Surg. 2015 May;100(5):836-40. doi: 10.9738/INTSURG-D-14-00141.1.
3
Characteristics and outcome of recurrence in molecularly defined adult-type ovarian granulosa cell tumors.分子定义的成人型卵巢颗粒细胞瘤复发的特征与结局
Gynecol Oncol. 2016 Dec;143(3):571-577. doi: 10.1016/j.ygyno.2016.10.002. Epub 2016 Oct 10.
4
Malignant solitary fibrous tumor of the greater omentum: A case report and review of literature.大网膜恶性孤立性纤维性肿瘤:1例病例报告并文献复习
World J Clin Cases. 2021 Jan 16;9(2):445-456. doi: 10.12998/wjcc.v9.i2.445.
5
Robot-assisted laparoscopic debulking surgery for recurrent adult granulosa cell tumors.机器人辅助腹腔镜减瘤手术治疗复发性成人颗粒细胞瘤
Gynecol Oncol Rep. 2021 May 7;37:100783. doi: 10.1016/j.gore.2021.100783. eCollection 2021 Aug.
6
Adult Granulosa Cell Tumor With High-grade Transformation: Report of a Series With FOXL2 Mutation Analysis.成人颗粒细胞瘤伴高级别转化:伴有 FOXL2 突变分析的一系列病例报告。
Am J Surg Pathol. 2019 Sep;43(9):1229-1238. doi: 10.1097/PAS.0000000000001296.
7
Cystic lymphangioma of the greater omentum treated by laparoscopic resection.大网膜囊性淋巴管瘤经腹腔镜切除治疗。
Clin J Gastroenterol. 2021 Aug;14(4):1004-1007. doi: 10.1007/s12328-021-01404-8. Epub 2021 Mar 29.
8
First Account of Primary Leiomyosarcoma of the Lesser Omentum since Establishment of c-Kit Mutations in Gastrointestinal Stromal Tumors.自胃肠道间质瘤中c-Kit突变确立以来小网膜原发性平滑肌肉瘤的首例报道
Case Rep Surg. 2019 Nov 4;2019:2426092. doi: 10.1155/2019/2426092. eCollection 2019.
9
Primary Omental Lipoma in a Child: A Case Report and Literature Review.儿童原发性网膜脂肪瘤:一例报告及文献综述
Front Pediatr. 2022 Jan 28;9:820845. doi: 10.3389/fped.2021.820845. eCollection 2021.
10
Laparoscopic examination and resection for giant lipoma of the omentum: a case report and review of related literature.腹腔镜检查及大网膜巨大脂肪瘤切除术:一例报告并文献复习
Surg Laparosc Endosc Percutan Tech. 2009 Oct;19(5):e217-20. doi: 10.1097/SLE.0b013e3181b97edd.

引用本文的文献

1
Successful laparoscopic cytoreductive surgery for multiple (three) advanced recurrences of AGCT in a young woman. A case report.一名年轻女性多次(三次)晚期复发性无性细胞瘤的成功腹腔镜细胞减灭术。病例报告。
Int J Surg Case Rep. 2025 Feb;127:110960. doi: 10.1016/j.ijscr.2025.110960. Epub 2025 Jan 27.
2
Open-label phase II clinical trial of orteronel (TAK-700) in metastatic or advanced non-resectable granulosa cell ovarian tumors: the Greko II study (GETHI2013-01).奥替诺隆(TAK-700)用于转移性或晚期不可切除性卵巢颗粒细胞瘤的开放标签II期临床试验:Greko II研究(GETHI2013-01)
Clin Transl Oncol. 2024 Dec 30. doi: 10.1007/s12094-024-03827-4.
3

本文引用的文献

1
Omental Micrometastasis in Endometrial Cancer.子宫内膜癌的大网膜微转移。
Oncol Res Treat. 2019;42(9):466-469. doi: 10.1159/000501727. Epub 2019 Jul 24.
2
Diagnostic performance of imaging-guided core needle biopsy of the mesentery and peritoneum.肠系膜和腹膜的影像引导下粗针穿刺活检的诊断性能
Radiologia (Engl Ed). 2018 Mar-Apr;60(2):128-135. doi: 10.1016/j.rx.2017.12.003. Epub 2018 Feb 1.
3
Prognostic factors for recurrence in early stage adult granulosa cell tumor of the ovary.早期成年卵巢颗粒细胞瘤复发的预后因素
The Surgical Odyssey: A Case Report on Rare Isolated Abdominal Wall Recurrence in an Adult Ovarian Granulosa Cell Tumor.
手术历程:一例成人卵巢颗粒细胞瘤罕见孤立性腹壁复发的病例报告
Cureus. 2024 Nov 28;16(11):e74708. doi: 10.7759/cureus.74708. eCollection 2024 Nov.
Arch Gynecol Obstet. 2016 Nov;294(5):1031-1036. doi: 10.1007/s00404-016-4135-5. Epub 2016 Jun 20.
4
A recurrent granulosa cell tumor of the ovary 25 years after the initial diagnosis: A case report.初次诊断25年后复发性卵巢颗粒细胞瘤:一例报告
Int J Surg Case Rep. 2015;12:7-10. doi: 10.1016/j.ijscr.2015.05.004. Epub 2015 May 7.
5
Ovarian granulosa cell tumor: clinical features, treatment, outcome, and prognostic factors.卵巢颗粒细胞瘤:临床特征、治疗、结局及预后因素。
N Am J Med Sci. 2014 Mar;6(3):133-8. doi: 10.4103/1947-2714.128475.
6
Recurrence of adult granulosa cell tumor of the ovary: experience at a tertiary care center.卵巢成人颗粒细胞瘤的复发:三级保健中心的经验。
Ann Diagn Pathol. 2014 Jun;18(3):125-8. doi: 10.1016/j.anndiagpath.2014.02.002. Epub 2014 Feb 11.
7
Prognostic predictors and spread patterns in adult ovarian granulosa cell tumors: a multicenter long-term follow-up study of 108 patients.成人卵巢颗粒细胞瘤的预后预测因素及扩散模式:一项对108例患者的多中心长期随访研究
Int J Clin Oncol. 2014 Oct;19(5):912-20. doi: 10.1007/s10147-013-0630-x. Epub 2013 Oct 29.
8
A late recurring and easily forgotten tumor: ovarian granulosa cell tumor.一种迟发、易被遗忘的肿瘤:卵巢颗粒细胞瘤。
World J Surg Oncol. 2012 May 16;10:85. doi: 10.1186/1477-7819-10-85.
9
A long-term follow-up study of 176 cases with adult-type ovarian granulosa cell tumors.176 例成人型卵巢颗粒细胞瘤的长期随访研究。
Gynecol Oncol. 2012 Feb;124(2):244-9. doi: 10.1016/j.ygyno.2011.10.015. Epub 2011 Oct 20.
10
Clinicopathologic characteristics of granulosa cell tumors of the ovary: a multicenter retrospective study.卵巢颗粒细胞瘤的临床病理特征:一项多中心回顾性研究。
J Gynecol Oncol. 2011 Sep;22(3):188-95. doi: 10.3802/jgo.2011.22.3.188. Epub 2011 Sep 28.