Goethe J W, Szarek B L, Cook W L
Research Department, Institute of Living, Hartford, Connecticut 06106.
J Nerv Ment Dis. 1988 Aug;176(8):465-70. doi: 10.1097/00005053-198808000-00002.
The authors reviewed the records of 201 nonbipolar depressed inpatients to a) determine the level of somatic therapies prescribed and b) compare the characteristics and global outcomes of patients given "adequate" vs. "inadequate" treatment. A stepwise multiple regression analysis revealed that patients given higher levels of somatic therapy were significantly (p less than .001) more likely to be older and have depression with psychotic features and less likely to have compulsive personality disorders. These patients also had significantly longer hospitalizations. A separate stepwise regression analysis showed that patients given higher levels of somatic therapy had superior outcomes (p less than .001). The proportion of this sample given no antidepressant medication or electroconvulsive therapy (18.4%) and the proportion given "adequate" treatment (45.3% to 63.7%, depending on the criteria applied) were comparable to the findings of other published reports.
作者回顾了201名非双相抑郁住院患者的记录，以：a）确定所开具的躯体治疗水平；b）比较接受“充分”与“不充分”治疗的患者的特征及总体结局。逐步多元回归分析显示，接受更高水平躯体治疗的患者显著（p<0.001）更可能年龄较大，患有伴有精神病性特征的抑郁症，且患强迫性人格障碍的可能性较小。这些患者的住院时间也显著更长。另一项逐步回归分析表明，接受更高水平躯体治疗的患者结局更好（p<0.001）。该样本中未接受抗抑郁药物或电休克治疗的比例（18.4%）以及接受“充分”治疗的比例（45.3%至63.7%，取决于所应用的标准）与其他已发表报告的结果相当。
