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早期周围型肺癌与非结核分枝杆菌肺病之间的关联

[Association between early peripheral lung cancer and nontuberculous mycobacterial lung disease].

作者信息

Trakhanov I V, Filimonov P N, Cherednichenko A G, Yagubkin P A

机构信息

Novosibirsk Tuberculosis Research Institute, Novosibirsk, Russia.

出版信息

Arkh Patol. 2021;83(3):52-55. doi: 10.17116/patol20218303152.

DOI:10.17116/patol20218303152
PMID:34041897
Abstract

Mycobacteriosis is an infectious disease caused by nontuberculous mycobacteria, with granulomatous inflammation in the affected organs and tissues. The association of mycobacteriosis and lung cancer in one patient is quite rarely observed and is of interest to the medical community. A 63-year-old male patient was admitted to the hospital with a diagnosis of infiltrative tuberculosis in SI-SII of both lungs in the lung cavitation phase on the right, peripheral mass in SIII on the right in order to make a decision about a surgical intervention. Morphological examination of the material obtained during upper lobectomy revealed mucinous adenocarcinoma concurrent with mycobacterium-associated inflammation with cavern formation. A bacteriological study confirmed the presence of the pathogen . This study reports a case of association of the diseases with successful surgical intervention without complications in the early postoperative period.

摘要

分枝杆菌病是一种由非结核分枝杆菌引起的传染病,在受影响的器官和组织中会出现肉芽肿性炎症。一名患者同时患有分枝杆菌病和肺癌的情况极为罕见,受到了医学界的关注。一名63岁男性患者因诊断为双肺SI-SII浸润性肺结核,处于右肺空洞形成期,右肺SIII有外周肿块而入院,以便决定是否进行手术干预。对上叶切除术中获取的材料进行形态学检查发现,存在黏液腺癌并伴有分枝杆菌相关炎症及空洞形成。细菌学研究证实了病原体的存在。本研究报告了一例两种疾病并存且手术干预成功、术后早期无并发症的病例。

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