Department of Informatics, Bioengineering, Robotics and System Engineering.
Department of Health Sciences, University of Genoa, Genoa, Italy.
Stud Health Technol Inform. 2021 May 27;281:1081-1082. doi: 10.3233/SHTI210354.
Invasive candidiasis is associated with high morbidity and mortality in critically ill patients, i.e. patients admitted to Intensive Care Units (ICUs) or in surgical wards. There are no clinical signs or specific symptoms and even though early diagnosis risk scores and rapid tests are available, none of such strategies has an equally-optimal level of sensitivity and specificity. In the era of Electronic Health Records (EHRs), several clinical studies exploited Machine Learning (ML) models and large database of features to improve the diagnosis accuracy. The main aim of this work is to build a wide dataset which can be exploited to apply ML models to further improve the early recognition of candidemia at the bedside of patients with compatible signs and symptoms.
侵袭性念珠菌病与重症患者(即入住重症监护病房或外科病房的患者)的高发病率和死亡率相关。目前没有临床体征或特定症状,尽管有早期诊断风险评分和快速检测方法,但这些策略的灵敏度和特异性都没有达到同样的最佳水平。在电子健康记录(EHR)时代,多项临床研究利用机器学习(ML)模型和大型特征数据库来提高诊断准确性。这项工作的主要目的是建立一个广泛的数据集,可用于应用 ML 模型,以进一步提高对有相符体征和症状的患者的床边念珠菌血症的早期识别。