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Detection and treatment of hypercholesterolemia in a biethnic community, 1979-1985.

作者信息

Pugh J A, Stern M P, Haffner S M, Hazuda H P, Patterson J

机构信息

Department of Medicine, University of Texas Health Science Center at San Antonio.

出版信息

J Gen Intern Med. 1988 Jul-Aug;3(4):331-6. doi: 10.1007/BF02595790.

DOI:10.1007/BF02595790
PMID:3404294
Abstract

Although hypercholesterolemia has been recognized as a risk factor for coronary heart disease (CHD) for decades, only in recent years have clinical trials definitively shown the efficacy of lowering serum cholesterol to prevent the occurrence or worsening of CHD. In 1985, an NIH consensus conference published guidelines for the diagnosis and treatment of hypercholesterolemia. Prior to 1985, physicians and lay people alike were not yet convinced of the necessity to know one's cholesterol level, nor did they know what levels should be treated. In a community-based survey of cardiovascular risk factors, known as the San Antonio Heart Study, in which 1,932 Mexican-Americans (MAs) and 1,133 non-Hispanic whites (NHWs) were examined between 1979 and 1985, the authors found that only 36/501 MAs (7%) and 54/312 NHWs (17%) in the moderate- or high-risk categories were aware that their cholesterols were high. Of the total number aware, including those whose cholesterol levels were in the low-risk range, only 23/97 MAs (24%) and 29/108 NHWs (27%) were receiving dietary or drug treatment. Of those being treated, only 9/23 MAs (39%) and 12/29 NHWs (41%) were effectively controlled. Mexican-Americans were less likely to be aware of their hypercholesterolemia than non-Hispanic whites, but both ethnic groups had low levels of treatment.

摘要

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本文引用的文献

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Epidemiologic aspects of coronary artery disease.冠状动脉疾病的流行病学方面
J Chronic Dis. 1957 Nov;6(5):552-9. doi: 10.1016/0021-9681(57)90043-7.
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The diet and the development of coronary heart disease.饮食与冠心病的发展
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Ethnic differences in health knowledge and behaviors related to the prevention and treatment of coronary heart disease. The San Antonio Heart Study.与冠心病防治相关的健康知识和行为的种族差异。圣安东尼奥心脏研究。
Am J Epidemiol. 1983 Jun;117(6):717-28. doi: 10.1093/aje/117.6.717.
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JAMA. 1984 Jan 20;251(3):351-64. doi: 10.1001/jama.1984.03340270029025.
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Serum cholesterol, lipoproteins, and the risk of coronary heart disease. The Framingham study.血清胆固醇、脂蛋白与冠心病风险。弗雷明汉姆研究。
Ann Intern Med. 1971 Jan;74(1):1-12. doi: 10.7326/0003-4819-74-1-1.