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使用正压通气治疗阻塞性睡眠呼吸暂停的体验:系统评价和主题综合分析。

Experiences of using positive airway pressure for treatment of obstructive sleep apnea: a systematic review and thematic synthesis.

机构信息

Lancaster University, Lancaster, UK.

出版信息

Sleep. 2021 Oct 11;44(10). doi: 10.1093/sleep/zsab135.

DOI:10.1093/sleep/zsab135
PMID:34043010
Abstract

STUDY OBJECTIVES

Suboptimal use of positive airway pressure (PAP) to treat obstructive sleep apnea (OSA) continues to be a major challenge to effective treatment. Meanwhile, the individual and societal impacts of untreated OSA make effective treatment a priority. Although extensive research has been conducted into factors that impact PAP use, it is estimated that at least half of users do not use it as prescribed. However, the voice of users is notably minimal in the literature. A systematic review and qualitative metasynthesis of PAP user experience was conducted to contribute to understandings of how PAP is experienced and to inform how usage could be improved.

METHODS

PsycINFO, MEDLINE, CINAHL, and EMBASE databases were systematically searched. Primary research findings of adult experiences using PAP that had been inductively analyzed were included. Papers were critically appraised using the CASP qualitative checklist to generate a "hierarchy of evidence." Thematic synthesis was then conducted to generate analytical themes. Results were presented in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA).

RESULTS

Twenty-five papers reporting on over 398 people's experiences were analyzed to generate four themes: Journey to PAP, Discomfort from and around PAP, Adapting to and using PAP, and Benefits from PAP. Author reflexivity and vulnerability to bias is acknowledged.

CONCLUSIONS

The findings highlight the applicability of a biopsychosocial understanding to PAP use. This metasynthesis gave voice to user experiences, revealing barriers to PAP use at a healthcare service level across the world, and suggests ways services can address these barriers. PROSPERO registration number: CRD42020157767.

摘要

研究目的

治疗阻塞性睡眠呼吸暂停(OSA)时,正压通气(PAP)的使用不理想仍然是有效治疗的主要挑战。同时,未经治疗的 OSA 对个人和社会的影响使得有效治疗成为当务之急。尽管已经对影响 PAP 使用的因素进行了广泛的研究,但据估计,至少有一半的使用者没有按照规定使用 PAP。然而,在文献中,使用者的声音明显很少。对 PAP 用户体验进行了系统评价和定性荟萃分析,以帮助了解 PAP 的使用体验,并为如何改善使用情况提供信息。

方法

系统检索了 PsycINFO、MEDLINE、CINAHL 和 EMBASE 数据库。纳入了对使用 PAP 的成年人经验进行归纳分析的原始研究结果。使用 CASP 定性清单对论文进行批判性评估,生成“证据层次结构”。然后进行主题综合以生成分析主题。结果按照系统评价和荟萃分析的首选报告项目(PRISMA)呈现。

结果

分析了 25 篇报告超过 398 人经验的论文,生成了四个主题:使用 PAP 的历程、PAP 带来的不适和周围问题、适应和使用 PAP、以及 PAP 的益处。承认作者的反思性和易受偏见的影响。

结论

研究结果强调了将生物心理社会理解应用于 PAP 使用的适用性。该荟萃分析为用户体验发声,揭示了全球范围内医疗保健服务层面上使用 PAP 的障碍,并提出了服务可以解决这些障碍的方法。PROSPERO 注册号:CRD42020157767。

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Experiences of using positive airway pressure for treatment of obstructive sleep apnea: a systematic review and thematic synthesis.使用正压通气治疗阻塞性睡眠呼吸暂停的体验:系统评价和主题综合分析。
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