Mansell Stephanie K, Gowing Francesca, Hilton Stephen T, Main Eleanor, Mandal Swapna, Schievano Silvia, Kilbride Cherry
University College London Institute of Cardiovascular Science, London, UK
Therapy Services, Royal Free London NHS Foundation Trust, London, UK.
BMJ Open. 2025 May 6;15(5):e093622. doi: 10.1136/bmjopen-2024-093622.
Sleep disordered breathing is a chronic condition often requiring patient commitment to positive airway pressure (PAP) therapy. Understanding the lived experience of PAP therapy users is crucial for clinicians to support successful treatment and identify research priorities. There is a lack of evidence in this area, and published data predominantly explore the negative experiences of PAP. This study aims to explore the lived experiences of patients using PAP therapy.
This study employs a phenomenological approach, appropriate for researching human experiences where there is little existing research. Heideggerian theory underpins the research, recognising that the researcher's beliefs influence meaning, allowing for rich analysis of the lived experience.Participants will be recruited from a randomised controlled trial investigating the medium-term clinical impact of customised interfaces for patients requiring PAP therapy. Purposive sampling will be used to seek representation from various demographics, with a maximum of 30 participants.Data collection will be via 1:1 semistructured interviews. Data will be analysed using Braun and Clarke's six-phase reflexive thematic analysis. Data will be analysed inductively through an interpretivism lens. Data will be managed with computer-assisted qualitative data analysis software.
This protocol has been approved by the Hampshire B Research Ethics Committee (REC reference: 22/SC/0405). Results will be disseminated to healthcare professionals and patients through conferences, open-access journals, newsletters, the study webpage, infographics, animations, social media and healthcare awards. Tracy's eight 'big tent' criteria for excellent qualitative research are comprehensive and encompassing, and this protocol has aimed to meet the criteria. The Consolidated Criteria for Reporting Qualitative Research has also been used. The findings of this study will contribute to a more holistic understanding of the lived experience of PAP therapy users, informing clinical practice and future research.
ISRCTN74082423.
睡眠呼吸障碍是一种慢性病，通常需要患者坚持使用气道正压通气（PAP）治疗。了解PAP治疗使用者的实际体验对于临床医生支持成功治疗并确定研究重点至关重要。该领域缺乏证据，已发表的数据主要探讨了PAP的负面体验。本研究旨在探索使用PAP治疗的患者的实际体验。
本研究采用现象学方法，适用于对现有研究较少的人类体验进行研究。海德格尔理论为该研究提供了支撑，认识到研究者的信念会影响意义，从而能够对实际体验进行深入分析。参与者将从一项随机对照试验中招募，该试验旨在研究定制接口对需要PAP治疗的患者的中期临床影响。将采用目的抽样法从不同人口统计学特征中选取代表，最多30名参与者。数据收集将通过一对一的半结构化访谈进行。数据将使用布劳恩和克拉克的六阶段反思性主题分析法进行分析。数据将通过解释主义视角进行归纳分析。数据将使用计算机辅助定性数据分析软件进行管理。
本方案已获得汉普郡B研究伦理委员会批准（伦理审查委员会参考号：22/SC/0405）。研究结果将通过会议、开放获取期刊、时事通讯、研究网页、信息图表、动画、社交媒体和医疗保健奖项等方式传播给医疗专业人员和患者。特蕾西的优秀定性研究的八个“大框架”标准全面且具有包容性，本方案旨在符合这些标准。还使用了《定性研究报告统一标准》。本研究的结果将有助于更全面地了解PAP治疗使用者的实际体验，为临床实践和未来研究提供参考。
ISRCTN74082423。
