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Methotrexate and interstitial lung disease. Is there a real causative factor?

作者信息

Pelechas E, Georgiadis A N, Voulgari P V, Drosos A A

机构信息

Rheumatology Clinic, Department of Internal Medicine, Medical School, University of Ioannina, 45110, Ioannina, Greece.

出版信息

Rheumatol Int. 2021 Nov;41(11):2045-2046. doi: 10.1007/s00296-021-04901-8. Epub 2021 May 27.

DOI:10.1007/s00296-021-04901-8
PMID:34043045
Abstract
摘要

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Does methotrexate cause progressive fibrotic interstitial lung disease? A systematic review.甲氨蝶呤是否会导致进行性纤维化间质性肺病？系统评价。
Rheumatol Int. 2021 Jun;41(6):1055-1064. doi: 10.1007/s00296-020-04773-4. Epub 2021 Jan 29.
2
Treatment strategies are more important than drugs in the management of rheumatoid arthritis.在类风湿关节炎的治疗中，治疗策略比药物更重要。
Clin Rheumatol. 2020 Apr;39(4):1363-1368. doi: 10.1007/s10067-020-05001-x. Epub 2020 Feb 22.
3
Progressive Decline of Lung Function in Rheumatoid Arthritis-Associated Interstitial Lung Disease.
类风湿关节炎相关间质性肺疾病肺功能进行性下降。
Arthritis Rheumatol. 2017 Mar;69(3):542-549. doi: 10.1002/art.39971.
4
Prevalence of airway and parenchymal abnormalities in newly diagnosed rheumatoid arthritis.新诊断类风湿关节炎患者的气道和实质异常的患病率。
Respir Med. 2012 Oct;106(10):1441-6. doi: 10.1016/j.rmed.2012.06.020. Epub 2012 Jul 13.
5
Brief report: airways abnormalities and rheumatoid arthritis-related autoantibodies in subjects without arthritis: early injury or initiating site of autoimmunity?简短报告：无关节炎受试者的气道异常与类风湿关节炎相关自身抗体：自身免疫的早期损伤还是起始部位？
Arthritis Rheum. 2012 Jun;64(6):1756-61. doi: 10.1002/art.34344. Epub 2011 Dec 19.
6
Pulmonary abnormalities in patients with early and longstanding rheumatoid arthritis.早期和长期类风湿性关节炎患者的肺部异常
J Rheumatol. 2009 Feb;36(2):444-5; author reply 445-6. doi: 10.3899/jrheum.080882.
7
Comparison of pulmonary abnormalities on high-resolution computed tomography in patients with early versus longstanding rheumatoid arthritis.早期与长期类风湿关节炎患者高分辨率计算机断层扫描肺部异常情况的比较。
J Rheumatol. 2008 Aug;35(8):1513-21. Epub 2008 Jun 15.
8
Pulmonary involvement in patients with early rheumatoid arthritis.早期类风湿关节炎患者的肺部受累情况。
Scand J Rheumatol. 2007 Sep-Oct;36(5):338-44. doi: 10.1080/03009740701393957.
9
Extra-articular disease manifestations in rheumatoid arthritis: incidence trends and risk factors over 46 years.类风湿关节炎的关节外疾病表现：46年期间的发病率趋势及危险因素
Ann Rheum Dis. 2003 Aug;62(8):722-7. doi: 10.1136/ard.62.8.722.
10
Airways involvement in rheumatoid arthritis: clinical, functional, and HRCT findings.类风湿关节炎中的气道受累：临床、功能及高分辨率CT表现
Am J Respir Crit Care Med. 1998 May;157(5 Pt 1):1658-65. doi: 10.1164/ajrccm.157.5.9710018.