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开放和血管内修复腹主动脉瘤的量效关系:2006-2018 年行政数据。

Volume-outcome relationships in open and endovascular repair of abdominal aortic aneurysm: administrative data 2006-2018.

机构信息

School of Health and Related Research, University of Sheffield, Sheffield, UK.

Sheffield Vascular Institute, Sheffield Teaching Hospitals, Sheffield, UK.

出版信息

Br J Surg. 2021 May 27;108(5):521-527. doi: 10.1002/bjs.11919.

Abstract

BACKGROUND

The aim of this study was to use recent evidence to investigate and update volume-outcome relationships after open surgical repair (OSR) and endovascular repair (EVAR) of abdominal aortic aneurysm in England.

METHODS

Hospital Episode Statistics (HES) data from April 2006 to March 2018 were obtained. The primary outcome was in-hospital death. Other outcomes included duration of hospital stay, readmissions within 30 days, and critical care requirements. Case-mix adjustment included age, sex, HES year, deprivation index, weekend admission, mode of admission, type of procedure and co-morbidities.

RESULTS

Annual volume of all repairs combined appeared to be an appropriate measure of volume. After case-mix adjustment, a significant relationship between volume and in-hospital mortality was seen for OSR (P < 0·001) but not for EVAR (P = 0·169 for emergency and P = 0·363 for elective). The effect appeared to extend beyond 60 repairs per year to volumes above 100 repairs per year. There was no significant relationship between volume and duration of hospital stay or 30-day readmissions. In patients receiving emergency OSR, higher volume was associated with longer stay in critical care.

CONCLUSION

Higher annual all-procedure volumes were associated with significantly lower in-hospital mortality for OSR, but such a relationship was not significant for EVAR. There was not enough evidence for a volume effect on other outcomes.

摘要

背景

本研究旨在利用最新证据调查和更新英格兰开放性手术修复(OSR)和血管内修复(EVAR)治疗腹主动脉瘤的量效关系。

方法

获取了 2006 年 4 月至 2018 年 3 月的医院病例统计数据(HES)。主要结局指标为住院期间死亡。其他结局指标包括住院时间、30 天内再入院和重症监护需求。病例组合调整包括年龄、性别、HES 年份、贫困指数、周末入院、入院方式、手术类型和合并症。

结果

所有修复手术的年度总量似乎是衡量手术量的一个合适指标。经过病例组合调整后,OSR 的手术量与住院死亡率之间存在显著关系(P<0·001),但 EVAR 则没有(急诊 P=0·169,择期 P=0·363)。这种效应似乎超出了每年 60 例手术的范围,扩展到了每年 100 例以上。手术量与住院时间或 30 天再入院之间没有显著关系。在接受紧急 OSR 的患者中,更高的手术量与更长时间的重症监护停留相关。

结论

更高的年度总手术量与 OSR 的住院死亡率显著降低相关,但 EVAR 则没有显著的相关性。对于其他结局,没有足够的证据表明存在量效关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bde7/10364891/3f6b00a328a0/znaa179f1.jpg

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