Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Department of Psychology, Arizona State University, Tempe, Arizona, USA.
Pain Med. 2021 Oct 8;22(10):2162-2173. doi: 10.1093/pm/pnab173.
The present study had three primary objectives. First, pain trajectory from early childhood to early adolescence were modeled. Second, we examined how early childhood individual-, parental-, and family-level factors predict pain trajectories. Third, we evaluated consequences of pain trajectories in terms of anxiety and depressive symptoms, and substance use at age 16 years.
The current paper is a secondary data analysis of a multisite longitudinal study. A total of 731 children and their families were followed from ages 2 to 16 years.
A growth mixture model (GMM) was used to identify pain trajectories from ages 2 to 14 years.
The GMM revealed three distinct pain trajectories: (1) Low Pain Symptom (n = 572); (2) Increasing Pain Symptom (n = 106); and (3) U-shaped Pain Symptom (n = 53). Children who experienced greater harsh parenting and sleep disturbances in early childhood were more likely to belong to the Increasing Pain Symptom group, and those with greater anxious-depressed symptoms at age 2 years were more likely to belong to the U-shaped Pain Symptom group than the Low Pain Symptom group. Additionally, those youth in the Increasing Pain Symptom group, compared to the Low and U-shaped Pain Symptom groups, showed elevated anxiety symptoms at age 16 years.
Reducing harsh parenting and children's sleep disturbances could be important targets for preventing pediatric pain problems. Children with increasing pain symptoms may also benefit from learning adaptive pain management skills to lower the risk of developing anxiety problems in late adolescence.
本研究有三个主要目标。首先,对儿童早期至青少年早期的疼痛轨迹进行建模。其次,我们研究了儿童早期个体、父母和家庭层面的因素如何预测疼痛轨迹。第三,我们评估了疼痛轨迹在 16 岁时的焦虑和抑郁症状以及物质使用方面的后果。
本文是一项多地点纵向研究的二次数据分析。共有 731 名儿童及其家庭从 2 岁到 16 岁接受了随访。
使用增长混合模型(GMM)来识别从 2 岁到 14 岁的疼痛轨迹。
GMM 揭示了三种不同的疼痛轨迹:(1)低疼痛症状(n=572);(2)疼痛症状逐渐增加(n=106);和(3)U 形疼痛症状(n=53)。在儿童早期经历更多严厉的养育方式和睡眠障碍的儿童更有可能属于疼痛症状逐渐增加的群体,而在 2 岁时表现出更多焦虑抑郁症状的儿童更有可能属于 U 形疼痛症状的群体,而不是低疼痛症状的群体。此外,与低疼痛症状和 U 形疼痛症状群体相比,处于疼痛症状逐渐增加群体的青少年在 16 岁时表现出更高的焦虑症状。
减少严厉的养育方式和儿童的睡眠障碍可能是预防儿科疼痛问题的重要目标。疼痛症状逐渐增加的儿童也可能受益于学习适应性疼痛管理技能,以降低在青少年晚期出现焦虑问题的风险。