Rejuvenation Res. 2021 Jun;24(3):238-243. doi: 10.1089/rej.2021.0028.
Theses reviewed in this issue include "Engineering Protein Disaggregases to Counter Alpha-Synuclein and Amyloid-Beta Neurotoxicity," "Hyperglycaemia Induced Immunomodulation of Macrophages in Diabetic Vascular Disease," "Microvasculature-on-a-Chip Systems for Human Disease Modeling," "Senescence Surveillance: The Interplay Between the Immune System and Senescent Cells," "The HMG Transcription Factor TOX Induces a Transcriptional and Epigenetic Program of CD8 T Cell Exhaustion in Chronic Infection and Cancer," and "Zero to One-Translational Advancements in the Field of Xenotransplantation."
本期评论包括“工程蛋白去聚集物以对抗α-突触核蛋白和淀粉样-β神经毒性”、“糖尿病血管疾病中高血糖诱导的巨噬细胞免疫调节”、“用于人类疾病建模的微血管芯片系统”、“衰老监测:免疫系统与衰老细胞的相互作用”、“HMG 转录因子 TOX 在慢性感染和癌症中诱导 CD8 T 细胞耗竭的转录和表观遗传程序”和“异种移植领域的从零到一的转化进展。”