Zealley Benjamin
SENS Research Foundation, 110 Pioneer Way, Suite J, Mountain View, CA 94041.
Rejuvenation Res. 2021 Dec;24(6):464-469. doi: 10.1089/rej.2021.0079.
Theses reviewed in this issue include "A Rapid Lipid-Based Approach for Normalization of Quantum Dot-Detected Biomarker Expression on Extracellular Vesicles in Complex Biological Samples," "Cancer Dynamics Under a Chemotherapeutic Stress Gradient Using a Microfluidic Tumor Environment," "Cells Exhibiting Strong P16ink4a Promoter Activation Display Features of Senescence," "HLA-G Dimer Prolongs Kidney Allograft Survival by Inhibiting CD8 T Cell Activation and Granzyme B Expression," "Lysophosphatidic Acid Suppression of CD8 T Cell Signaling and Function," and "Targeting Therapeutic T Cells to the Bone Marrow Niche."
本期综述的论文包括《一种基于脂质的快速方法用于复杂生物样品中细胞外囊泡上量子点检测的生物标志物表达的标准化》《使用微流控肿瘤环境研究化疗应激梯度下的癌症动态》《表现出强P16ink4a启动子激活的细胞显示衰老特征》《HLA-G二聚体通过抑制CD8 T细胞活化和颗粒酶B表达延长肾移植存活时间》《溶血磷脂酸对CD8 T细胞信号传导和功能的抑制作用》以及《将治疗性T细胞靶向骨髓生态位》。