Hughson A V, Cooper A F, McArdle C S, Smith D C
University Department of Psychological Medicine, Glasgow, U.K.
J Psychosom Res. 1988;32(2):173-80. doi: 10.1016/0022-3999(88)90052-9.
Psychosocial morbidity was compared in 91 patients awaiting breast biopsy and 30 women awaiting elective cholecystectomy. Somatic symptoms and social dysfunction were prominent in cholecystectomy patients. Patients subsequently found to have benign breast disease had the highest levels of psychological morbidity. Patients found to have breast cancer appeared no more anxious or depressed than those awaiting cholecystectomy. However, within the breast cancer group, patients aged 45 or less were significantly more anxious than those over 45, and a past history of psychological upset, prior to discovery of breast disease, was positively and independently associated with anxiety. Results are consistent with recent research suggesting an association between benign breast disease and a predisposition to psychological morbidity.
对91名等待乳房活检的患者和30名等待择期胆囊切除术的女性的心理社会发病率进行了比较。胆囊切除术患者的躯体症状和社会功能障碍较为突出。随后被发现患有良性乳腺疾病的患者心理发病率最高。被发现患有乳腺癌的患者似乎并不比等待胆囊切除术的患者更焦虑或抑郁。然而,在乳腺癌组中,45岁及以下的患者比45岁以上的患者明显更焦虑,并且在发现乳腺疾病之前有心理困扰的既往史与焦虑呈正相关且独立相关。结果与最近的研究一致,该研究表明良性乳腺疾病与心理发病率的易感性之间存在关联。