由引发酶合成的RNA引物，用于启动噬菌体G4 DNA复制。
The RNA primer synthesized by primase to initiate phage G4 DNA replication.
作者信息
Bouché J P, Rowen L, Kornberg A
出版信息
J Biol Chem. 1978 Feb 10;253(3):765-9.
PMID:340458
Abstract
With phage G4 DNA as template, primase (the dnaG protein) synthesizes a 26- to 29-residue RNA transcript at the origin of replication. The sequence starts with ATP and contains a hairpin region of one A-U and seven G-C base pairs. Covalent linkage between the RNA and the newly synthesized complementary DNA chain indicates that the RNA transcript serves as a primer.
摘要
以噬菌体G4 DNA为模板，引发酶（dnaG蛋白）在复制起点合成一段26至29个残基的RNA转录本。该序列以ATP起始，包含一个由一个A-U和七个G-C碱基对组成的发夹区域。RNA与新合成的互补DNA链之间的共价连接表明RNA转录本充当引物。
Zotero 插件