Zampieri Nicola, Corato Valentina, Scirè Gabriella, Camoglio Francesco Saverio
Department of Surgery, Dentistry, Paediatrics and Gynecology, Woman and Child Hospital; Division of Pediatric Surgery, University of Verona, Verona, Italy.
Pediatr Gastroenterol Hepatol Nutr. 2021 May;24(3):265-272. doi: 10.5223/pghn.2021.24.3.265. Epub 2021 May 4.
Hypertrophic pyloric stenosis (HPS) is the most common cause of gastric obstruction in newborns. Extra-mucosal pyloromyotomy can be performed through a small laparotomy or laparoscopy. The aim of this study was to compare the two surgical techniques. We also analyzed the incidence of HPS in infants in the last 10 years in relation to the demographic trend of our province.
We analyzed all the cases of HPS treated at our Unit between January 2010 and December 2019. The data were obtained from operating systems. Data about the demographic trends, in particular, the number of births and the population residing in the province of Verona from 2010 to 2019, were also retrieved.
During the study period, 60 patients were treated for HPS and met the inclusion criteria. Of these, 56 males and 4 females with an average age of 38±14 days at surgery were included. No differences were found in terms of the duration of surgery, post-operative complications, duration of hospitalization, and weight at the time of surgery. The only statistically significant data was the chlorine level in cases with and without post-operative vomiting (97±3.5 vs. 102±3.3 mmol/L, <0.05). There was a lower incidence of HPS from 2014 to 2019; however, there was no significant evidence regarding the correlation between this and the reduced birth rate recorded in the province of Verona during the same period.
Although laparoscopic pyloromyotomy is a highly complex procedure, it is a feasible alternative to the classic open technique.
肥厚性幽门狭窄(HPS)是新生儿胃梗阻最常见的原因。粘膜外幽门肌切开术可通过小切口剖腹手术或腹腔镜手术进行。本研究的目的是比较这两种手术技术。我们还分析了过去10年中该省婴儿肥厚性幽门狭窄的发病率与人口统计学趋势的关系。
我们分析了2010年1月至2019年12月在本单位接受治疗的所有肥厚性幽门狭窄病例。数据来自手术系统。还检索了有关人口统计学趋势的数据,特别是2010年至2019年维罗纳省的出生人数和常住人口。
在研究期间,60例肥厚性幽门狭窄患者接受治疗并符合纳入标准。其中包括56例男性和4例女性,手术时平均年龄为38±14天。在手术时间、术后并发症、住院时间和手术时体重方面未发现差异。唯一具有统计学意义的数据是术后呕吐和未呕吐病例的氯水平(97±3.5 vs. 102±3.3 mmol/L,<0.05)。2014年至2019年肥厚性幽门狭窄的发病率较低;然而,没有显著证据表明这与同期维罗纳省记录的出生率下降之间存在相关性。
尽管腹腔镜幽门肌切开术是一种高度复杂的手术,但它是经典开放技术的一种可行替代方案。