Wang Zhi-Heng, Zhang Meng-Pei, Zhang Hao-Xiang, Pan Jie, Zuo Kai-Ni, Wang Xiao-Mei, Zhu Wen-Tao
School of Management, Beijing University of Chinese Medicine Beijing 100029, China.
Zhongguo Zhong Yao Za Zhi. 2021 May;46(10):2588-2593. doi: 10.19540/j.cnki.cjcmm.20200910.501.
To evaluate the economics of Suhuang Zhike Capsules in the treatment of acute exacerbation of chronic obstructive pulmonary disease(AECOPD) for inpatients. Based on the published clinical research data, cost-utility analysis was used in this study to evaluate the pharmacoeconomics of Suhuang Zhike Capsules in treatment of AECOPD inpatients from the perspective of medical insu-rance. The test group was treated with Suhuang Zhike Capsules combined with conventional Western medicine, and the control group was treated with conventional Western medicine alone. Treeage software was used to construct a pharmacoeconomic model and perform simulation analysis. The results showed that the cost and output of Suhuang Zhike Capsules combined with the conventional Western medicine were 60 010.18 yuan and 1.92 quality adjusted life year(QALYs), respectively in the simulated 3 years of disease treatment. The cost and output of the conventional Western medicine were 96 730.60 yuan and 1.90 QALYs respectively. Suhuang Zhike Capsules combined with conventional Western medicine required lower cost but achieved higher output, showing cost-utility advantages, so this drug combination was a plan with pharmacoeconomic advantages. The sensitivity analysis results showed that the conclusion was relatively stable. Based on the above results, it is believed that as compared with the conventional Western medicine, Suhuang Zhike Capsules combined with conventional Western medicine have lower cost and higher output for the treatment of AECOPD inpatients, and it is a treatment plan with pharmacoeconomic advantages.
评估苏黄止咳胶囊治疗慢性阻塞性肺疾病急性加重期(AECOPD)住院患者的经济学效果。基于已发表的临床研究数据,本研究采用成本-效用分析从医疗保险角度评估苏黄止咳胶囊治疗AECOPD住院患者的药物经济学。试验组采用苏黄止咳胶囊联合西医常规治疗,对照组采用单纯西医常规治疗。运用Treeage软件构建药物经济学模型并进行模拟分析。结果显示,在模拟的3年疾病治疗中,苏黄止咳胶囊联合西医常规治疗的成本和产出分别为60010.18元及1.92个质量调整生命年(QALYs)。西医常规治疗的成本和产出分别为96730.60元及1.90个QALYs。苏黄止咳胶囊联合西医常规治疗成本更低但产出更高,显示出成本-效用优势,因此该药物联合方案是具有药物经济学优势的方案。敏感性分析结果表明结论相对稳定。基于上述结果,认为与西医常规治疗相比,苏黄止咳胶囊联合西医常规治疗AECOPD住院患者成本更低、产出更高,是具有药物经济学优势的治疗方案。