Mizukami Takuro, Piao Yongzhe
Department of Clinical Oncology, St. Marianna University, Kawasaki, 216-8511, Japan.
Eli Lilly Japan K.K., Kobe, 651-0086, Japan.
Future Oncol. 2021 Aug;17(23):3101-3109. doi: 10.2217/fon-2021-0186. Epub 2021 May 28.
Patients with advanced or metastatic gastric cancer often suffer from malnutrition, which can have an impact on quality of life, increase the toxicity of chemotherapy and reduce overall survival. Options available to the clinician to manage a patient's nutritional status include screening and assessment of malnutrition at diagnosis, monitoring during the 'cancer journey', early detection of precachexia and the ongoing use of a multidisciplinary team (oncologists, other medical specialists and nutritionists). Because malnutrition is frequently overlooked and under treated in patients with advanced or metastatic gastric cancer, this narrative review focuses on the clinical meaning of nutritional status in gastric cancer and provides general guidance regarding nutritional care management for patients with advanced or metastatic gastric cancer.
晚期或转移性胃癌患者常伴有营养不良,这会影响生活质量,增加化疗毒性并缩短总生存期。临床医生可采用的管理患者营养状况的方法包括在诊断时筛查和评估营养不良情况、在“抗癌全程”中进行监测、早期发现恶病质前期以及持续启用多学科团队(肿瘤学家、其他医学专家和营养师)。由于晚期或转移性胃癌患者的营养不良常常被忽视且治疗不足,本文叙述性综述聚焦于胃癌营养状况的临床意义,并为晚期或转移性胃癌患者的营养护理管理提供一般性指导。