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小儿慢性危重病的发病率、特征及转归评估。

Evaluation of the incidence, characteristics, and outcomes of pediatric chronic critical illness.

作者信息

Demirkiran Hilmi, Kilic Mehmet, Tomak Yakup, Dalkiran Tahir, Yurttutan Sadik, Basaranoglu Murat, Tuncer Oguz, Derme Turan, Tekeli Arzu Esen, Bahar Ilhan, Keskin Siddik, Oksuz Hafize

机构信息

Department of Anesthesiology and Reanimation, Faculty of Medicine, Van Yuzuncu Yil University, Van, Turkey.

Department of Pediatrics, Hisar Intercontinental Hospital, Istanbul, Turkey.

出版信息

PLoS One. 2021 May 28;16(5):e0248883. doi: 10.1371/journal.pone.0248883. eCollection 2021.

Abstract

Our aim was to determine characteristics of children with chronic critical illness (CCI) admitted to the pediatric intensive care unit (PICU) of a tertiary care children's hospital in Turkey. The current study was a multicenter retrospective cohort study that was done from 2014 to 2017. It involved three university hospitals PICUs in which multiple criteria were set to identify pediatric CCIs. Pediatric patients staying in the ICU for at least 14 days and having at least one additional criterion, including prolonged mechanical ventilation, tracheostomy, sepsis, severe wound (burn) or trauma, encephalopathy, traumatic brain injury, status epilepticus, being postoperative, and neuromuscular disease, was accepted as CCI. In order to identify the newborn as a chronic critical patient, a stay in the intensive care unit for at least 30 days in addition to prematurity was required. Eight hundred eighty seven (11.14%) of the patients who were admitted to the PICU met the definition of CCI and 775 of them (87.3%) were discharged to their home. Of CCI patients, 289 (32.6%) were premature and 678 (76.4%) had prolonged mechanical ventilation. The total cost values for 2017 were statistically higher than the other years. As the length of ICU stay increased, the costs also increased. Interestingly, high incidence rates were observed for PCCI in our hospitals and these patients occupied 38.01% of the intensive care bed capacity. In conclusion, we observed that prematurity and prolonged mechanical ventilation increase the length of ICU stay, which also increased the costs. More work is needed to better understand PCCI.

摘要

我们的目的是确定入住土耳其一家三级儿童医院儿科重症监护病房(PICU)的慢性危重病(CCI)患儿的特征。本研究为多中心回顾性队列研究,时间跨度为2014年至2017年。研究涉及三家大学医院的PICU,设定了多项标准来识别儿科CCI。在ICU住院至少14天且有至少一项附加标准的儿科患者被认定为CCI,附加标准包括长时间机械通气、气管切开术、败血症、严重伤口(烧伤)或创伤、脑病、创伤性脑损伤、癫痫持续状态、术后状态以及神经肌肉疾病。为了将新生儿认定为慢性危重病患者,除早产外还需在重症监护病房住院至少30天。入住PICU的患者中有887例(11.14%)符合CCI的定义,其中775例(87.3%)出院回家。在CCI患者中,289例(32.6%)为早产儿,678例(76.4%)有长时间机械通气。2017年的总费用值在统计学上高于其他年份。随着ICU住院时间的延长,费用也随之增加。有趣的是,我们医院中PCCI的发病率较高,这些患者占用了38.01%的重症监护床位。总之,我们观察到早产和长时间机械通气会增加ICU住院时间,这也会增加费用。需要开展更多工作以更好地了解PCCI。

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