TB Modelling Group, TB Centre and Centre for Mathematical Modelling of Infectious Diseases, Department of Infectious Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine (LSHTM), London, UK.
Department of Global Health Development, Faculty of Public Health and Policy, LSHTM, London, UK.
Int J Tuberc Lung Dis. 2021 Jun 1;25(6):436-446. doi: 10.5588/ijtld.21.0148.
Early in the COVID-19 pandemic, models predicted hundreds of thousands of additional TB deaths as a result of health service disruption. To date, empirical evidence on the effects of COVID-19 on TB outcomes has been limited. Here we summarise the evidence available at a country level, identifying broad mechanisms by which COVID-19 may modify TB burden and mitigation efforts. From the data, it is clear that there have been substantial disruptions to TB health services and an increase in vulnerability to TB. Evidence for changes in transmission is limited, and it remains unclear how the resources required and available for the TB response have changed. To advocate for additional funding to mitigate the impact of COVID-19 on the global TB burden, and to efficiently allocate resources for the TB response, requires a significant improvement in the TB data available.
在 COVID-19 大流行早期,模型预测由于卫生服务中断,将有数十万人死于结核病。迄今为止,关于 COVID-19 对结核病结果影响的经验证据有限。在这里,我们总结了在国家层面上可用的证据,确定了 COVID-19 可能改变结核病负担和缓解工作的广泛机制。从这些数据中可以清楚地看出,结核病卫生服务受到了严重干扰,结核病的易感性也有所增加。关于传播变化的证据有限,也不清楚为结核病应对所需和可用的资源发生了怎样的变化。为了倡导增加资金以减轻 COVID-19 对全球结核病负担的影响,并为结核病应对有效分配资源,需要大大改进现有的结核病数据。