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无乳链球菌——一种可能被忽视的病原体,可引起新生儿败血症,而常规 B 群链球菌筛查并未涵盖此类疾病。

Streptococcus gallolyticus - A potentially neglected pathogen causing neonatal sepsis not covered by routine group B streptococcus screening.

机构信息

Department of Pediatrics, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taiwan.

Department of Pediatrics, Chi Mei Medical Center, Tainan, Taiwan; Department of Biotechnology and Food Technology, Southern Taiwan University of Science and Technology, Tainan, Taiwan.

出版信息

J Microbiol Immunol Infect. 2021 Dec;54(6):1190-1192. doi: 10.1016/j.jmii.2021.05.003. Epub 2021 May 15.

DOI:10.1016/j.jmii.2021.05.003
PMID:34052145
Abstract

We report 4 cases of neonatal sepsis caused by Streptococcus gallolyticus. The clinical course was quite similar to early-and late-onset group B streptococcus disease. None of the mothers had group B streptococcus (GBS) colonization on prenatal screening nor received intrapartum antibiotics. We proposed the sporadic distribution of S. gallolyticus sepsis among neonates was partly due to relatively low colonization rate in adults compared with GBS. Species determination of S. gallolyticus may not be available using conventional microbiological methods and may contribute to underestimation or misclassification. In our series, we highlighted the importance of S. gallolyticus as an important pathogen in neonatal sepsis deserving further surveillance.

摘要

我们报告了 4 例由鹑鸡肠球菌引起的新生儿败血症。临床过程与早发型和晚发型 B 组链球菌病非常相似。这些母亲在产前筛查时均无 B 组链球菌(GBS)定植,也未接受产时抗生素治疗。我们提出,与 GBS 相比,成年人的鹑鸡肠球菌定植率相对较低,导致新生儿鹑鸡肠球菌败血症呈散发性分布。使用常规微生物学方法可能无法确定鹑鸡肠球菌的种类,这可能导致低估或分类错误。在我们的系列研究中,我们强调了鹑鸡肠球菌作为新生儿败血症的重要病原体的重要性,值得进一步监测。

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