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学校重新开放对 COVID-19 在英国传播的影响。

The impact of school reopening on the spread of COVID-19 in England.

机构信息

The Zeeman Institute for Systems Biology and Infectious Disease Epidemiology Research, School of Life Sciences and Mathematics InstituteUniversity of Warwick, Coventry CV4 7AL, UK.

Joint UNIversities Pandemic and Epidemiological Research, https://maths.org/juniper/, University of Warwick, Coventry CV4 7AL, UK.

出版信息

Philos Trans R Soc Lond B Biol Sci. 2021 Jul 19;376(1829):20200261. doi: 10.1098/rstb.2020.0261. Epub 2021 May 31.

Abstract

By mid-May 2020, cases of COVID-19 in the UK had been declining for over a month; a multi-phase emergence from lockdown was planned, including a scheduled partial reopening of schools on 1 June 2020. Although evidence suggests that children generally display mild symptoms, the size of the school-age population means the total impact of reopening schools is unclear. Here, we present work from mid-May 2020 that focused on the imminent opening of schools and consider what these results imply for future policy. We compared eight strategies for reopening primary and secondary schools in England. Modifying a transmission model fitted to UK SARS-CoV-2 data, we assessed how reopening schools affects contact patterns, anticipated secondary infections and the relative change in the reproduction number, . We determined the associated public health impact and its sensitivity to changes in social distancing within the wider community. We predicted that reopening schools with half-sized classes or focused on younger children was unlikely to push above one. Older children generally have more social contacts, so reopening secondary schools results in more cases than reopening primary schools, while reopening both could have pushed above one in some regions. Reductions in community social distancing were found to outweigh and exacerbate any impacts of reopening. In particular, opening schools when the reproduction number is already above one generates the largest increase in cases. Our work indicates that while any school reopening will result in increased mixing and infection amongst children and the wider population, reopening schools alone in June 2020 was unlikely to push above one. Ultimately, reopening decisions are a difficult trade-off between epidemiological consequences and the emotional, educational and developmental needs of children. Into the future, there are difficult questions about what controls can be instigated such that schools can remain open if cases increase. This article is part of the theme issue 'Modelling that shaped the early COVID-19 pandemic response in the UK'.

摘要

截至 2020 年 5 月中旬,英国的 COVID-19 病例已持续下降一个多月;计划分阶段逐步解除封锁,包括计划于 2020 年 6 月 1 日部分重新开放学校。尽管有证据表明儿童通常表现出轻微症状,但学龄人口的规模意味着重新开放学校的总体影响尚不清楚。在这里,我们展示了 2020 年 5 月中旬的工作,重点关注即将重新开放的学校,并考虑这些结果对未来政策的影响。我们比较了英格兰小学和中学重新开放的八种策略。通过修改适用于英国 SARS-CoV-2 数据的传播模型,我们评估了重新开放学校如何影响接触模式、预期的二次感染以及繁殖数的相对变化, 。我们确定了相关的公共卫生影响及其对更广泛社区内社会隔离变化的敏感性。我们预测,将班级规模减半或重点放在年幼孩子身上的重新开放不太可能使 超过 1。年龄较大的儿童通常有更多的社会接触,因此重新开放中学比重新开放小学导致更多的病例,而同时重新开放两者在某些地区可能使 超过 1。我们发现,社区社会隔离的减少会超过并加剧重新开放的任何影响。特别是,当繁殖数 已经超过 1 时,重新开放学校会导致病例的最大增加。我们的工作表明,尽管任何学校重新开放都会导致儿童和更广泛人群之间的混合和感染增加,但 2020 年 6 月单独重新开放学校不太可能使 超过 1。最终,重新开放的决定是在流行病学后果和儿童的情感、教育和发展需求之间进行艰难的权衡。未来,有一些棘手的问题是关于可以实施哪些控制措施,以便在病例增加的情况下保持学校开放。本文是“塑造英国早期 COVID-19 大流行应对措施的建模”主题特刊的一部分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e23a/8165595/b1cf1a79bf63/rstb20200261f01.jpg

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