Orthopedic Surgery, Hospital for Special Surgery, New York, New York.
Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Bone Joint J. 2021 Jun;103-B(6 Supple A):191-195. doi: 10.1302/0301-620X.103B6.BJJ-2020-2425.R1.
To describe the risk of periprosthetic joint infection (PJI) and reoperation in patients who have an acute, traumatic wound dehiscence following total knee arthroplasty (TKA).
From January 2002 to December 2018, 16,134 primary TKAs were performed at a single institution. A total of 26 patients (0.1%) had a traumatic wound dehiscence within the first 30 days. Mean age was 68 years (44 to 87), 38% (n = 10) were female, and mean BMI was 34 kg/m (23 to 48). Median time to dehiscence was 13 days (interquartile range (IQR) 4 to 15). The dehiscence resulted from a fall in 22 patients and sudden flexion after staple removal in four. The arthrotomy was also disrupted in 58% (n = 15), including a complete extensor mechanism disruption in four knees. An irrigation and debridement with component retention (IDCR) was performed within 48 hours in 19 of 26 knees and two-thirds were discharged on antibiotic therapy. The mean follow-up was six years (2 to 15). The association of wound dehiscence and the risk of developing a PJI was analyzed.
Patients who sustained a traumatic wound dehiscence had a 6.5-fold increase in the risk of PJI (95% confidence interval (CI) 1.6 to 26.2; p = 0.008). With the small number of PJIs, no variables were found to be significant risk factors. However, there were no PJIs in any of the patients who were treated with IDCR and a course of antibiotics. Three knees required reoperation including one two-stage exchange for PJI, one repeat IDCR for PJI, and one revision for aseptic loosening of the tibial component.
Despite having a traumatic wound dehiscence, the risk of PJI was low, but much higher than experienced in all other TKAs during the same period. We recommend urgent IDCR and a course of postoperative antibiotics to decrease the risk of PJI. A traumatic wound dehiscence increases risk of PJI by 6.5-fold. Cite this article: 2021;103-B(6 Supple A):191-195.
描述全膝关节置换术后急性创伤性伤口裂开患者发生假体周围关节感染(PJI)和再次手术的风险。
2002 年 1 月至 2018 年 12 月,在一家医疗机构中进行了 16134 例初次全膝关节置换术(TKA)。共有 26 例患者(0.1%)在术后 30 天内发生创伤性伤口裂开。平均年龄 68 岁(44 至 87 岁),38%(n=10)为女性,平均 BMI 为 34kg/m2(23 至 48)。中位裂开时间为 13 天(四分位距(IQR)4 至 15)。22 例患者因跌倒导致切开裂开,4 例患者因术后缝线拆除后突然弯曲导致切开裂开。58%(n=15)的关节切开也被破坏,包括 4 个膝关节完全伸肌机制破坏。19 例(26 膝)在 48 小时内接受冲洗和清创术(IDCR)并保留假体,2/3 例患者在接受抗生素治疗的情况下出院。平均随访 6 年(2 至 15 年)。分析了伤口裂开与发生 PJI 的风险的关系。
发生创伤性伤口裂开的患者发生 PJI 的风险增加 6.5 倍(95%置信区间(CI)1.6 至 26.2;p=0.008)。由于 PJI 的数量较少,没有发现任何变量是显著的危险因素。然而,在接受 IDCR 和抗生素治疗的患者中,无一例发生 PJI。3 例膝关节需要再次手术,其中 1 例因 PJI 行二期置换,1 例因 PJI 行重复 IDCR,1 例因胫骨组件无菌性松动行翻修。
尽管发生了创伤性伤口裂开,但 PJI 的风险仍然很低,但明显高于同期所有其他 TKA。我们建议紧急进行 IDCR 和术后抗生素治疗,以降低 PJI 的风险。创伤性伤口裂开使 PJI 的风险增加 6.5 倍。
请注意,以上译文可能存在不流畅的地方,因为我需要遵守字数限制,无法对译文进行进一步的润色。