PediMIND Program, Mclean Hospital, 115 Mill Street, Belmont, MA, USA; Simches Center of Excellence in Child and Adolescent Psychiatry, McLean Hospital, Harvard Medical School.
PediMIND Program, Mclean Hospital, 115 Mill Street, Belmont, MA, USA; Simches Center of Excellence in Child and Adolescent Psychiatry, McLean Hospital, Harvard Medical School.
Child Adolesc Psychiatr Clin N Am. 2021 Jul;30(3):649-666. doi: 10.1016/j.chc.2021.04.013.
Irritability is a common reason why children and adolescents are brought for psychiatric care. Although research is advancing what is known about the underlying brain and behavior mechanisms of irritability, clinicians often are shut out of that research. This article explains some of these research methods, providing brief summaries of what is known about brain/behavior mechanisms in disorders involving irritability, including bipolar disorder, disruptive mood dysregulation disorder, attention-deficit/hyperactivity disorder, and autism spectrum disorder. Greater access to these methods may help clinicians now and in the future, with such mechanisms translated into improved care, as occurs in the treatment of childhood leukemia.
易激惹是儿童和青少年寻求精神科护理的常见原因。尽管研究正在深入了解易激惹的潜在大脑和行为机制，但临床医生通常无法参与该研究。本文解释了其中一些研究方法，简要总结了涉及易激惹的疾病（包括双相情感障碍、破坏性情绪失调障碍、注意缺陷/多动障碍和自闭症谱系障碍）的大脑/行为机制的已知情况。更多地使用这些方法可能有助于临床医生现在和将来更好地进行治疗，就像在治疗儿童白血病时，将这些机制转化为改善治疗一样。
