Cellular and Molecular Research Center, Research Institute for Health Development, Research Institute for Health Development, Kurdistan University of Medical Sciences, Iran.
Department of Microbiology, School of Medicine, Hamadan University of Medical Sciences, Iran.
Jpn J Infect Dis. 2022 Jan 24;75(1):1-4. doi: 10.7883/yoken.JJID.2021.006. Epub 2021 May 31.
Neisseria gonorrhoeae is the causative agent of the sexually transmitted disease gonorrhoea. This bacterium infects the epithelial cells of the cervix of women and the urethra of men. However, its disease symptoms in the lower genitalia are found only in a small percentage of people. This study aimed to compare the frequency of N. gonorrhoeae genital infection among two groups of pregnant women, those with spontaneous abortions and those with normal pregnancies. This cross-sectional study was conducted in Western Iran. It included 417 women: 109 of whom had spontaneous abortions, 109 had normal deliveries, 100 were fertile, and 99 were infertile. Specific primers were used and DNA was extracted by endocervical swabs. A polymerase chain reaction test was then performed to detect N. gonorrhoeae. Data analysis was performed using the chi-squared test and t-tests. In all the above steps, a level of 5% was considered statistically significant, and the average ages in women with normal delivery, women with spontaneous abortion, fertile women, and infertile women were 27.8 ± 4.87, 29.6 ± 5.9, 32.1 ± 5.1, and 29.1 ± 6.3 years, respectively. The total frequency of N. gonorrhoeae infection was 0 (0%). The prevalence of N. gonorrhoeae infection was zero, and the disease was not associated with spontaneous abortion or infertility.
淋病奈瑟菌是性传播疾病淋病的病原体。这种细菌感染女性宫颈和男性尿道的上皮细胞。然而,其在下生殖道的疾病症状仅在一小部分人群中发现。本研究旨在比较两组孕妇(自然流产组和正常妊娠组)中淋病奈瑟菌生殖器感染的频率。这项横断面研究在伊朗西部进行。它包括 417 名妇女:109 名自然流产,109 名正常分娩,100 名生育能力正常,99 名生育能力异常。使用特定的引物并通过宫颈拭子提取 DNA。然后进行聚合酶链反应试验以检测淋病奈瑟菌。使用卡方检验和 t 检验进行数据分析。在所有上述步骤中,统计显著性水平设为 5%,正常分娩妇女、自然流产妇女、生育能力正常妇女和生育能力异常妇女的平均年龄分别为 27.8 ± 4.87 岁、29.6 ± 5.9 岁、32.1 ± 5.1 岁和 29.1 ± 6.3 岁。淋病奈瑟菌总感染率为 0(0%)。淋病奈瑟菌感染的患病率为零,该疾病与自然流产或不孕无关。