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转诊至妇产科诊所的女性中淋球菌和非淋球菌感染的患病率。

The prevalence of gonococcal and non-gonococcal infections in women referred to obstetrics and gynecology clinics.

作者信息

Kazemian Hossein, Zarandi Morteza Karami, Zargoush Zeinab, Ghafourian Sobhan, Sadeghifard Nourkhoda, Jalilian Anahita, Shafieian Mahnaz, Pakzad Iraj

机构信息

Department of Microbiology, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran.

Clinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam, Iran.

出版信息

Infez Med. 2022 Jun 1;30(2):247-253. doi: 10.53854/liim-3002-10. eCollection 2022.

Abstract

Bacterial vaginosis is a condition caused by changes in the vaginal microbial ecosystem and increases the risk of preterm delivery, premature rupture of membranes, endometritis, and weight loss of the baby. This study aimed to evaluate the frequency of gonococcal and non-gonococcal genital infections in women referred to clinics in Ilam, Iran. Two swab samples were taken from each patient using a sterile swab, one swab was placed in a THB medium for the culture of and the other in PBS buffer for PCR. PCR method was conducted for the identification of the other bacterial agents such as , , , , , and also . Sampling was performed on 169 women with symptomatic vaginosis. The frequency of by culture and PCR methods was 4.7% (8 samples) and 13.6% (23 samples) respectively. Also, 6.5% (11 samples), 3.5% (6 samples), 4.1% (7 samples), 1.2% (2 samples), and 0% of the samples were positive for , , , and by PCR method. Except for a significant association between colonization and abortion, there was no significant correlation between the prevalence of these bacteria and the patient's age, age of marriage, number of deliveries, and number of abortions. Overall, the prevalence of gonococcal and non-gonococcal infection in women referred to clinics in Ilam is similar to the other parts of Iran.

摘要

细菌性阴道病是一种由阴道微生物生态系统变化引起的病症,会增加早产、胎膜早破、子宫内膜炎和婴儿体重减轻的风险。本研究旨在评估转诊至伊朗伊拉姆诊所的女性中淋球菌和非淋球菌性生殖道感染的发生率。使用无菌拭子从每位患者采集两份拭子样本,一份拭子置于THB培养基中用于培养,另一份置于PBS缓冲液中用于PCR检测。采用PCR方法鉴定其他细菌病原体,如 、 、 、 、 以及 。对169例有症状性阴道病的女性进行了采样。通过培养和PCR方法检测 的发生率分别为4.7%(8份样本)和13.6%(23份样本)。此外,通过PCR方法检测,样本中 、 、 、 和 的阳性率分别为6.5%(11份样本)、3.5%(6份样本)、4.1%(7份样本)、1.2%(2份样本)和0%。除 定植与流产之间存在显著关联外,这些细菌的流行率与患者年龄、结婚年龄、分娩次数和流产次数之间均无显著相关性。总体而言,转诊至伊拉姆诊所的女性中淋球菌和非淋球菌感染的发生率与伊朗其他地区相似。

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