Ferrara A, Perrella A, Cavallaro G F, Rondelli R
Cattedra di Fisiopatologia Respiratoria, Università degli Studi di Milano.
Minerva Med. 1988 Jul;79(7):509-16.
On earlier occasions healthy subjects, and chronic bronchopneumopathy patients were subjected to respiratory function tests in different postures using the plethysmographic and helium dilution methods. This protocol was then applied to a series of obese patients without the functional characteristics of alveolar hypoventilation identified in preliminary functional tests. The study revealed: a) non significant differences between plethysmographic and helium dilution findings; b) no significant volumetric differences produced by different postures (standing or squatting) especially as far as Total Lung Capacity is concerned. These results confirm the findings of others (Sharp et al., 1986) that diaphragmatic adjustment to changes in posture is inadequate in the obese even in the absence of hypoventilation.
在早期，健康受试者和慢性支气管肺病患者曾使用体积描记法和氦稀释法在不同体位下进行呼吸功能测试。然后将该方案应用于一系列肥胖患者，这些患者在初步功能测试中未发现肺泡通气不足的功能特征。研究发现：a）体积描记法和氦稀释法的结果之间无显著差异；b）不同体位（站立或蹲位）产生的容积差异不显著，尤其是就肺总量而言。这些结果证实了其他人（夏普等人，1986年）的发现，即即使在没有通气不足的情况下，肥胖者膈肌对体位变化的调节也不足。
