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补充乙酸:对静息和运动能量消耗及底物利用的影响。

Acetic Acid Supplementation: Effect on Resting and Exercise Energy Expenditure and Substrate Utilization.

作者信息

Cobb Kolton M, Chavez Domenico A, Kenyon Jonathan D, Hutelin Zach, Webster Michael J

机构信息

School of Health Sciences, Valdosta State University, Valdosta, GA, USA.

出版信息

Int J Exerc Sci. 2021 Apr 1;14(2):222-229. doi: 10.70252/GUNG6262. eCollection 2021.

DOI:10.70252/GUNG6262
PMID:34055150
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8136602/
Abstract

The purpose of this study was to investigate the influence of acetic acid (apple cider vinegar; ACV) supplementation on resting and exercise energy expenditure and substrate utilization. Using a randomized, double blind, crossover design, 16 healthy subjects were supplemented for 4 d with either ACV (30-ml/d) mixed in 1 L of a non-nutritive lemon-flavored drink or a placebo (PLA). They were then assessed via indirect calorimetry for resting energy expenditure (REE) and substrate utilization. This was immediately followed by the assessment of steady state cycling exercise energy expenditure at 40 W (EEE-40) and 80 W (EEE-80) and substrate utilization. Results: Neither REE nor resting substrate utilization were significantly different between groups ( ≥ .05). During cycling exercise at both 40W and 80W, there were no significant differences observed between groups for energy expenditure (EEE-40: ACV 4.13 ± 0.79, PLA 4.37 ± 0.61 kcal/min; EEE-80: ACV 6.09 ± 0.87, PLA 6.26 ± 0.72 kcal/min) or substrate utilization (40W carbohydrate: ACV 0.72 ± 0.19, PLA 0.76 ± 0.16; fat: ACV 0.15 ± 0.07, PLA 0.16 ± 0.06 g/min), (80W carbohydrate: ACV 1.28 ± 0.32, PLA 1.34 ± 0.35; fat: ACV 0.14 ± 0.10, PLA 0.14 ± 0.10 g/min) ( ≥ .05). Conclusions: Recent findings suggest that chronic acetic acid supplementation is associated with significant reductions in body weight and body fat; however, the findings of the present study suggest that a semi-acute (4 d) acetic acid supplementation does not impact resting or exercise energy expenditure or substrate utilization.

摘要

本研究的目的是调查补充醋酸(苹果醋;ACV)对静息和运动能量消耗以及底物利用的影响。采用随机、双盲、交叉设计,16名健康受试者连续4天补充混入1升无营养柠檬味饮料中的ACV(30毫升/天)或安慰剂(PLA)。然后通过间接测热法评估他们的静息能量消耗(REE)和底物利用情况。紧接着评估40瓦(EEE - 40)和80瓦(EEE - 80)稳态循环运动能量消耗及底物利用情况。结果:两组之间的REE和静息底物利用均无显著差异(P≥0.05)。在40瓦和80瓦的循环运动中,两组之间在能量消耗(EEE - 40:ACV组4.13±0.79,PLA组4.37±0.61千卡/分钟;EEE - 80:ACV组6.09±0.87,PLA组6.26±0.72千卡/分钟)或底物利用方面(40瓦时碳水化合物:ACV组0.72±0.19,PLA组0.76±0.16;脂肪:ACV组0.15±0.07,PLA组0.16±0.06克/分钟),(80瓦时碳水化合物:ACV组1.28±0.32,PLA组1.34±0.35;脂肪:ACV组0.14±0.10,PLA组0.14±0.10克/分钟)均未观察到显著差异(P≥0.05)。结论:近期研究结果表明,长期补充醋酸与体重和体脂显著降低有关;然而,本研究结果表明,半急性(4天)补充醋酸不会影响静息或运动能量消耗或底物利用。

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本文引用的文献

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Effect and mechanisms of action of vinegar on glucose metabolism, lipid profile, and body weight.醋对葡萄糖代谢、血脂谱和体重的影响及其作用机制。
Nutr Rev. 2014 Oct;72(10):651-61. doi: 10.1111/nure.12125. Epub 2014 Aug 28.
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Functional properties of vinegar.醋的功能特性。
J Food Sci. 2014 May;79(5):R757-64. doi: 10.1111/1750-3841.12434.
4
Influence of the tolerability of vinegar as an oral source of short-chain fatty acids on appetite control and food intake.醋作为短链脂肪酸口服来源的耐受性对食欲控制和食物摄入量的影响。
Int J Obes (Lond). 2014 May;38(5):675-81. doi: 10.1038/ijo.2013.157. Epub 2013 Aug 27.
5
A single oral administration of acetic acid increased energy expenditure in C57BL/6J mice.单次口服醋酸可增加C57BL/6J小鼠的能量消耗。
Biosci Biotechnol Biochem. 2010;74(10):2158-9. doi: 10.1271/bbb.100486. Epub 2010 Oct 7.
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Vinegar reduces postprandial hyperglycaemia in patients with type II diabetes when added to a high, but not to a low, glycaemic index meal.当添加到高血糖指数但不是低血糖指数的膳食中时,醋可降低 2 型糖尿病患者的餐后高血糖。
Eur J Clin Nutr. 2010 Jul;64(7):727-32. doi: 10.1038/ejcn.2010.89. Epub 2010 May 26.
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Vinegar intake enhances flow-mediated vasodilatation via upregulation of endothelial nitric oxide synthase activity.摄入醋通过上调内皮型一氧化氮合酶活性增强血流介导的血管舒张。
Biosci Biotechnol Biochem. 2010;74(5):1055-61. doi: 10.1271/bbb.90953. Epub 2010 May 7.
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Examination of the antiglycemic properties of vinegar in healthy adults.检测食醋对健康成年人的降血糖作用。
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Vinegar intake reduces body weight, body fat mass, and serum triglyceride levels in obese Japanese subjects.摄入醋可降低肥胖日本受试者的体重、体脂肪量和血清甘油三酯水平。
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Acetic acid upregulates the expression of genes for fatty acid oxidation enzymes in liver to suppress body fat accumulation.乙酸上调肝脏中脂肪酸氧化酶基因的表达,以抑制体脂积累。
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