Monks George, Rivera-Oyola Ryan, Lebwohl Mark
Dr. Monks is with the Department of Dermatology, University of Oklahoma College of Medicine in Oklahoma City, Oklahoma.
Mr. Rovera-Oyola and Dr. Lebwohl are with the Department of Dermatology, Icahn School of Medicine at Mt. Sinai Hospital in New York, New York.
J Clin Aesthet Dermatol. 2021 Apr;14(4):14-22. Epub 2021 Apr 1.
Psoriasis, an inflammatory disorder of the skin, is associated with an increased risk of systemic diseases, such as psoriatic arthritis, psychiatric disorders, malignancy, and cardiometabolic and inflammatory bowel diseases. Careful consideration of the presence of these comorbidities should guide selection of appropriate therapy. The evolution of therapeutic targets for the treatment of psoriasis has significantly advanced available treatment options, potentially leading to uncertainty when selecting the optimal treatment for each patient. In this article, we review evidence-based guidelines for the use of psoriasis treatments in patients with distinct comorbidities, and group appropriate therapeutic options into a visual aid. An easy-to-use visual tool incorporating treatment options best suited for specific comorbidities can increase physicians' confidence when selecting the most appropriate treatment on an individualized basis.
银屑病是一种皮肤炎症性疾病，与系统性疾病风险增加相关，如银屑病关节炎、精神疾病、恶性肿瘤以及心脏代谢疾病和炎症性肠病。仔细考虑这些合并症的存在应指导合适治疗方法的选择。银屑病治疗靶点的演变显著推进了可用的治疗选择，这可能导致为每位患者选择最佳治疗时产生不确定性。在本文中，我们回顾了针对患有不同合并症的银屑病患者使用治疗方法的循证指南，并将合适的治疗选择归纳成一种可视化工具。一个易于使用的、纳入最适合特定合并症治疗选择的可视化工具，可以增强医生在个体化基础上选择最合适治疗方法时的信心。
