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银屑病患者的系统性银屑病治疗与合并症:潜在风险与益处综述

Systemic Psoriasis Therapies and Comorbid Disease in Patients with Psoriasis: A Review of Potential Risks and Benefits.

作者信息

Mikhaylov Daniela, Hashim Peter W, Nektalova Tatyana, Goldenberg Gary

机构信息

Ms. Mikhaylov and Drs. Hashim, Nektalova, and Goldenberg are with the Department of Dermatology at the Icahn School of Medicine at Mount Sinai in New York, New York.

Dr. Goldenberg is also with Goldenberg Dermatology, PC, in New York, New York.

出版信息

J Clin Aesthet Dermatol. 2019 Jun;12(6):46-54. Epub 2019 Jun 1.

PMID:31360288
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6624011/
Abstract

Psoriasis is an inflammatory skin disease that is associated with many comorbidities. Several psoriasis treatments approved by the United States Food and Drug Administration have been shown to have beneficial effects on these comorbidities, while others might lead to an exacerbation of these conditions. In this article, we review studies of psoriasis treatments and their level of evidence for use in co-occurring diseases. An awareness of the multifaceted effects of certain psoriasis medications can enable physicians to provide more personalized treatment to their most complicated patients.

摘要

银屑病是一种与多种合并症相关的炎症性皮肤病。美国食品药品监督管理局批准的几种银屑病治疗方法已被证明对这些合并症有有益效果,而其他一些治疗方法可能会导致这些病情加重。在本文中,我们回顾了银屑病治疗方法及其在并发疾病中应用的证据水平的研究。了解某些银屑病药物的多方面影响可以使医生为最复杂的患者提供更个性化的治疗。

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本文引用的文献

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Tildrakizumab: First Global Approval.替度鲁单抗:全球首次获批。
Drugs. 2018 Jun;78(8):845-849. doi: 10.1007/s40265-018-0917-3.
2
Emerging therapies in psoriasis: a systematic review.银屑病的新兴疗法:一项系统综述。
Cutis. 2018 Mar;101(3S):5-9.
3
Psoriasis and risk of incident chronic kidney disease and end-stage renal disease: a systematic review and meta-analysis.银屑病与慢性肾脏病及终末期肾病发病风险:一项系统评价与荟萃分析
Int Urol Nephrol. 2018 Jul;50(7):1277-1283. doi: 10.1007/s11255-018-1868-z. Epub 2018 Apr 11.
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Risk Factors Affecting Adverse Effects of Cyclosporine A in a Real-World Psoriasis Treatment.影响环孢素A在实际银屑病治疗中不良反应的危险因素
Ann Dermatol. 2018 Apr;30(2):143-149. doi: 10.5021/ad.2018.30.2.143. Epub 2018 Feb 21.
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The effect of subcutaneous methotrexate on markers of metabolic syndrome in psoriatic patients - preliminary report.皮下注射甲氨蝶呤对银屑病患者代谢综合征标志物的影响——初步报告
Postepy Dermatol Alergol. 2018 Feb;35(1):53-59. doi: 10.5114/ada.2017.71358. Epub 2018 Feb 20.
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Ixekizumab treatment shows a neutral impact on cardiovascular parameters in patients with moderate-to-severe plaque psoriasis: Results from UNCOVER-1, UNCOVER-2, and UNCOVER-3.依奇珠单抗治疗对中重度斑块型银屑病患者的心血管参数无显著影响:UNCOVER-1、UNCOVER-2 和 UNCOVER-3 研究结果。
J Am Acad Dermatol. 2018 Jul;79(1):104-109.e8. doi: 10.1016/j.jaad.2018.02.074. Epub 2018 Mar 13.
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Management of psoriasis in patients with inflammatory bowel disease: From the Medical Board of the National Psoriasis Foundation.炎症性肠病患者的银屑病管理:来自全国银屑病基金会医学委员会。
J Am Acad Dermatol. 2018 Feb;78(2):383-394. doi: 10.1016/j.jaad.2017.06.043.
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