Bumgardner Adam L, Yuan Kyle, Chiu Alden V
Internal Medicine and Psychiatry Residency Program, National Capital Consortium, Bethesda, MD, USA.
F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
Oxf Med Case Reports. 2021 May 24;2021(5):omab019. doi: 10.1093/omcr/omab019. eCollection 2021 May.
Aphantasia, the loss of mental imagery, is a rare disorder and even more infrequent when acquired. No previous cases have been identified that were caused by transplant-related treatment. We describe a case of acquired aphantasia in a 62-year-old male with refractory IgG kappa multiple myeloma after receiving an autologous stem cell transplant (ASCT) following high-dose melphalan with a complicated hospital admission. The etiology of aphantasia remains unidentified, but we provide viable explanations to include direct effects from ASCT treatment and indirect effects from transplant-related complications.
想象缺失症,即失去心理意象,是一种罕见的病症,后天获得性的情况更为罕见。此前尚未发现由移植相关治疗导致的病例。我们描述了一例62岁男性后天性想象缺失症的病例,该患者患有难治性IgG κ型多发性骨髓瘤,在接受大剂量美法仑自体干细胞移植(ASCT)后出现复杂的住院情况。想象缺失症的病因仍未明确,但我们提供了一些合理的解释,包括ASCT治疗的直接影响以及移植相关并发症的间接影响。