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淋菌性菌血症继发的ICD部位感染:首例报告病例

ICD Pocket-Site Infection Secondary to Gonococcal Bacteremia: The First Reported Case.

作者信息

Ijaz Sardar Hassan, Jafry Ali Haider, Shahnawaz Areeba, Allee Mark

机构信息

Department of Cardiovascular Disease, Lahey Medical Center, 41 Mall Road, Burlington, MA 01805, USA.

800 Stanton L. Young Blvd, AAT 6300, Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma, OK 73105, USA.

出版信息

Case Rep Infect Dis. 2021 May 4;2021:9250967. doi: 10.1155/2021/9250967. eCollection 2021.

Abstract

INTRODUCTION

Cardiovascular implantable electronic devices (CIEDs) are being increasingly used in the primary and secondary prevention of malignant ventricular arrhythmias and conduction system disorders. Infectious complications associated with CIEDs include infective endocarditis, lead infections, and pocket-site infections, primarily involving species. Infective endocarditis is a rare but life-threatening complication of gonococcal bacteremia. We report the first case of a CIED pocket-site infection secondary to .

CASE

A 56-year-old male with a history of congestive heart failure status postimplantable cardioverter-defibrillator (ICD) insertion presented with a pocket-site swelling initially concerning for a hematoma which began to exhibit erythema and tenderness. The patient reported a history of high-risk sexual behavior. On presentation, he was afebrile and hemodynamically stable. Physical exam showed a 5 cm × 6 cm pocket-site swelling with overlying erythema. Labs revealed elevated ESR and CRP levels. Transthoracic and transesophageal echocardiography was concerning for infective endocarditis and lead vegetations. Blood cultures tested positive for . He underwent surgical debridement with complete ICD extraction and drainage of infected serosanguineous pocket fluid. Tissue cultures were negative, but isolation of in blood cultures confirmed it as the causative agent of the pocket-site infection in the absence of prior Gram-positive coverage. He was started on a prolonged course of ceftriaxone for 4 weeks with reimplantation of ICD at a different site after completion of treatment.

CONCLUSION

In patients with high-risk sexual behavior, gonococcal bacteremia can potentially lead to CIED infection. These individuals should be prudently evaluated for infective endocarditis or pocket-site infections as presenting complaints can be subtle.

摘要

引言

心血管植入式电子设备(CIEDs)越来越多地用于恶性室性心律失常和传导系统疾病的一级和二级预防。与CIEDs相关的感染并发症包括感染性心内膜炎、导线感染和囊袋部位感染,主要涉及 菌种。感染性心内膜炎是淋菌性菌血症罕见但危及生命的并发症。我们报告首例继发于 的CIED囊袋部位感染病例。

病例

一名56岁男性,有充血性心力衰竭病史,植入式心脏复律除颤器(ICD)植入术后,出现囊袋部位肿胀,最初怀疑是血肿,随后开始出现红斑和压痛。患者报告有高危性行为史。就诊时,他无发热,血流动力学稳定。体格检查显示囊袋部位有一个5厘米×6厘米的肿胀,伴有红斑。实验室检查显示血沉和CRP水平升高。经胸和经食管超声心动图检查提示感染性心内膜炎和导线赘生物。血培养检测 呈阳性。他接受了手术清创,完整取出ICD,并引流感染的血清样囊袋液体。组织培养为阴性,但血培养中分离出 ,在未进行先前革兰氏阳性菌覆盖的情况下,证实其为囊袋部位感染的病原体。他开始接受为期4周的头孢曲松长疗程治疗,治疗结束后在不同部位重新植入ICD。

结论

在有高危性行为的患者中,淋菌性菌血症可能导致CIED感染。这些个体应谨慎评估是否存在感染性心内膜炎或囊袋部位感染,因为其临床表现可能不明显。

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