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因输液港导管感染导致的播散性淋球菌感染

Disseminated Gonococcal Infection Due to a Mediport Catheter Infection.

作者信息

Malik Ambreen, Peniston Michael, Donaghue Jason, Johnson Leonard B

机构信息

Infectious Diseases, Ascension St. John Hospital, Detroit, USA.

Internal Medicine, Ascension St. John Hospital, Detroit, USA.

出版信息

Cureus. 2023 Nov 2;15(11):e48180. doi: 10.7759/cureus.48180. eCollection 2023 Nov.

Abstract

Gonorrhea is a sexually transmitted disease caused by and has a wide clinical spectrum that can range from asymptomatic to disseminated disease. Most women with gonorrhea are asymptomatic and if left untreated, it can lead to serious complications like pelvic inflammatory disease (PID) and infertility. Disseminated gonococcal infection (DGI) is usually characterized by dermatitis, tenosynovitis, and septic arthritis but rarely can also cause bacteremia, endovascular infections, osteomyelitis, and meningitis. Gonococcal bacteremia is regarded as a disseminated disease and is typically associated with infection of the mucosal surfaces such as the urethra, endocervix, and pharynx. This report, to the best of our knowledge, presents a case of DGI associated with a mediport catheter in a patient with breast cancer without any history of gonococcal symptoms. She was monogamous and denied any history of sexually transmitted infections. The patient presented with fever and chills associated with pain and purulent discharge from the mediport catheter site. The mediport catheter was removed, and antibiotics were initiated. Both blood and wound cultures grew . She completed a 10-day course of ceftriaxone and improved clinically with complete remission of her symptoms. A review of the literature on the reported cases of DGI associated with bacteremia and endovascular infections is also presented.

摘要

淋病是一种由[病原体未提及]引起的性传播疾病,临床谱广泛,可从无症状感染到播散性疾病。大多数淋病女性患者无症状,若不治疗,可导致严重并发症,如盆腔炎(PID)和不孕。播散性淋球菌感染(DGI)通常表现为皮炎、腱鞘炎和化脓性关节炎,但也很少可引起菌血症、血管内感染、骨髓炎和脑膜炎。淋球菌菌血症被视为一种播散性疾病,通常与尿道、宫颈内膜和咽部等粘膜表面感染有关。据我们所知,本报告介绍了一例乳腺癌患者发生的与输液港导管相关的DGI病例,该患者无任何淋病症状史。她实行一夫一妻制,否认有任何性传播感染史。患者出现发热、寒战,伴有输液港导管部位疼痛和脓性分泌物。输液港导管被移除,并开始使用抗生素。血液和伤口培养均培养出[病原体未提及]。她完成了为期10天的头孢曲松疗程,临床症状改善,症状完全缓解。本文还对已报道的与菌血症和血管内感染相关的DGI病例的文献进行了综述。

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