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发生于淋巴水肿肢体的坏死性筋膜炎。

Necrotizing Fasciitis Occurred in the Lymphedematous leg.

机构信息

JR Tokyo General Hospital, Tokyo, Japan.

出版信息

Int J Low Extrem Wounds. 2023 Sep;22(3):599-604. doi: 10.1177/15347346211023030. Epub 2021 May 31.

DOI:10.1177/15347346211023030
PMID:34057385
Abstract

Lymphedema is a chronic edema that sometimes occurs after treatment of gynecologic cancer, and cellulitis often occurs concomitantly with lymphedema. On the other hand, necrotizing fasciitis (NF) is a relatively rare, but life-threatening disease. The symptoms in cellulitis and NF are very similar. In this case report, we describe a case in which the diagnosis of NF in a lymphedematous limb was difficult. A 70-year-old woman had secondary lymphedema in bilateral legs and consulted our department. On the first day of lymphedema therapy, the patient complained of vomiting, diarrhea, and fever (37.7 °C) without local fever in the legs. She was diagnosed with acute gastroenteritis. On the next day, swelling and pain in her left leg occurred and her blood pressure was 59/44 mmHg. She was diagnosed with cellulitis accompanied by lower limb lymphedema and septic shock. On the second day, blisters appeared on the left leg, and computed tomography showed NF. We performed debridement under general anesthesia and her vital signs improved postoperatively. (B) was detected in blood culture, and we administered bixillin and clindamycin. Postoperatively, necrosis in the skin and fat around the left ankle gradually spread, and it took 5 months to complete epithelialization. The diagnosis was more difficult than usual NF because patients with lymphedema often experience cellulitis. Clinicians should always think of NF to avoid mortality due to delayed treatment. This case report was approved by the institutional ethics committee.

摘要

淋巴水肿是一种慢性水肿,有时在妇科癌症治疗后发生,并且常伴有蜂窝织炎。另一方面,坏死性筋膜炎(NF)是一种相对罕见但危及生命的疾病。蜂窝织炎和 NF 的症状非常相似。在本病例报告中,我们描述了一例在淋巴水肿肢体中诊断 NF 困难的病例。一名 70 岁女性双侧腿部继发淋巴水肿,来我院就诊。在淋巴水肿治疗的第一天,患者诉呕吐、腹泻和发热(37.7℃),但腿部无局部发热。她被诊断为急性肠胃炎。第二天,她的左腿出现肿胀和疼痛,血压为 59/44mmHg。她被诊断为伴有下肢淋巴水肿和感染性休克的蜂窝织炎。第二天,左腿出现水疱,计算机断层扫描显示 NF。我们在全身麻醉下进行清创术,术后生命体征改善。血液培养中检测到(B),我们给予青霉素和克林霉素。术后,左踝周围的皮肤和脂肪坏死逐渐扩散,需要 5 个月才能完全上皮化。由于淋巴水肿患者常发生蜂窝织炎,因此该诊断比通常的 NF 更困难。临床医生应始终考虑 NF,以避免因治疗延迟而导致死亡。本病例报告已获得机构伦理委员会的批准。

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